Menin: a scaffold protein that controls gene expression and cell signaling.
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Summary of emerging personalized medicine in neuroendocrine tumors: are we on track?Pancreatic Cancer, A Mis-interpreter of the Epigenetic LanguageA Review of the Scaffold Protein Menin and its Role in Hepatobiliary Pathology.Menin enhances c-Myc-mediated transcription to promote cancer progression"RAS"ling β cells to proliferate for diabetes: why do we need MEN?Menin: a tumor suppressor that mediates postsynaptic receptor expression and synaptogenesis between central neurons of Lymnaea stagnalis.Targeting β-catenin signaling for therapeutic intervention in MEN1-deficient pancreatic neuroendocrine tumours.Modulation by miR-29b of intestinal epithelium homoeostasis through the repression of menin translation.Challenges and opportunities in targeting the menin-MLL interaction.Consequence of Menin Deficiency in Mouse Adipocytes Derived by In Vitro DifferentiationThe Cell Death Inhibitor ARC Is Induced in a Tissue-Specific Manner by Deletion of the Tumor Suppressor Gene Men1, but Not Required for Tumor Development and Growth.Multiple Endocrine Neoplasia: Genetics and Clinical Management.Decoding the Molecular and Mutational Ambiguities of Gastroenteropancreatic Neuroendocrine Neoplasm Pathobiology.Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin.Diabetes mellitus--advances and challenges in human β-cell proliferation.Twenty years of menin: emerging opportunities for restoration of transcription in MEN1.miR-24 Inhibition Increases Menin Expression and Decreases Cholangiocarcinoma Proliferation.Tumor suppressor menin is required for subunit-specific nAChR α5 transcription and nAChR-dependent presynaptic facilitation in cultured mouse hippocampal neurons.Spatial Interplay between Polycomb and Trithorax Complexes Controls Transcriptional Activity in T LymphocytesH3K27 Methylation: A Focal Point of Epigenetic Deregulation in Cancer.Enhancer-Mediated Oncogenic Function of the Menin Tumor Suppressor in Breast Cancer.MicroRNA-142-3p, a novel target of tumor suppressor menin, inhibits osteosarcoma cell proliferation by down-regulation of FASN.Pathophysiology of Gastric NETs: Role of Gastrin and Menin.Multiple Endocrine Neoplasia and Hyperparathyroid-Jaw Tumor Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood.Two proteolytic fragments of menin coordinate the nuclear transcription and postsynaptic clustering of neurotransmitter receptors during synaptogenesis between Lymnaea neurons.Menin localization in cell membrane compartmentUse of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation.Regulation of NO synthesis, local inflammation, and innate immunity to pathogens by BET family proteins.A MEN1 pancreatic neuroendocrine tumour mouse model under temporal control.Germline and somatic genetic changes in multicentric tumors obtained from a patient with multiple endocrine neoplasia type 1.Translational Diagnostics and Therapeutics in Pancreatic Neuroendocrine Tumors.Overexpression of PY1289-HER3 in sporadic pulmonary carcinoid from patients bearing MEN1 gene variants.Menin-mediated regulation of miRNA biogenesis uncovers the IRS2 pathway as a target for regulating pancreatic beta cells.Novel mutation 928G>C of MEN1 gene in a familial multiple endocrine neoplasia type 1 case (MEN1) with co-existence of insulinoma and glucagonoma.The future: genetics advances in MEN1 therapeutic approaches and management strategies.Epigenetic regulation by the menin pathway.Menin Controls the Memory Th2 Cell Function by Maintaining the Epigenetic Integrity of Th2 Cells.Deletion of Menin in craniofacial osteogenic cells in mice elicits development of mandibular ossifying fibroma.Resistance promoting effects of ependymoma treatment revealed through genomic analysis of multiple recurrences in a single patient.Menin and PRMT5 suppress GLP1 receptor transcript and PKA-mediated phosphorylation of FOXO1 and CREB.
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Menin: a scaffold protein that controls gene expression and cell signaling.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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Menin: a scaffold protein that controls gene expression and cell signaling.
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Menin: a scaffold protein that controls gene expression and cell signaling.
@en
prefLabel
Menin: a scaffold protein that controls gene expression and cell signaling.
@en
P2093
P2860
P1476
Menin: a scaffold protein that controls gene expression and cell signaling.
@en
P2093
Austin Thiel
Smita Matkar
Xianxin Hua
P2860
P304
P356
10.1016/J.TIBS.2013.05.005
P577
2013-07-10T00:00:00Z