The therapeutic potential of GPR43: a novel role in modulating metabolic health.

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Treatment of type 2 diabetes by free Fatty Acid receptor agonists.Benefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis.Central Agonism of GPR120 Acutely Inhibits Food Intake and Food Reward and Chronically Suppresses Anxiety-Like Behavior in Mice.

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The therapeutic potential of GPR43: a novel role in modulating metabolic health.

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The therapeutic potential of GPR43: a novel role in modulating metabolic health.

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The therapeutic potential of GPR43: a novel role in modulating metabolic health.

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The therapeutic potential of GPR43: a novel role in modulating metabolic health.

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P1476

The therapeutic potential of GPR43: a novel role in modulating metabolic health

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Lauren M Cornall

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Michael L Mathai

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Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41

Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short chain fatty acids

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor

Narrative review: the role of leptin in human physiology: emerging clinical applications

A core gut microbiome in obese and lean twins

Leptin administration favors muscle mass accretion by decreasing FoxO3a and increasing PGC-1alpha in ob/ob mice

Cardiac substrate uptake and metabolism in obesity and type-2 diabetes: Role of sarcolemmal substrate transporters

Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids

Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

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s00018-013-1419-9

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4759-4770

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scholarly article

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10.1007/S00018-013-1419-9

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Andrew J. McAinch

Deanne H Hryciw

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2013-07-14T00:00:00Z

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23852543

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The therapeutic potential of GPR43: a novel role in modulating metabolic health.

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P2860

P2860

The therapeutic potential of GPR43: a novel role in modulating metabolic health.

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