Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer.
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Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.The evidence for natural therapeutics as potential anti-scarring agents in burn-related scarringPreparation of lung-targeting, emodin-loaded polylactic acid microspheres and their properties.Screening of a natural compound library identifies emodin, a natural compound from Rheum palmatum Linn that inhibits DPP4.Luteolin inhibits behavioral sensitization by blocking methamphetamine-induced MAPK pathway activation in the caudate putamen in miceEmodin suppresses pulmonary metastasis of breast cancer accompanied with decreased macrophage recruitment and M2 polarization in the lungs.Novel synthetic biscoumarins target tumor necrosis factor-α in hepatocellular carcinoma in vitro and in vivo.The Role of Nutraceuticals in Pancreatic Cancer Prevention and Therapy: Targeting Cellular Signaling, MicroRNAs, and Epigenome.Inhibition of mechanical stress-induced hypertrophic scar inflammation by emodin.Phenotype-driven chemical screening in zebrafish for compounds that inhibit collective cell migration identifies multiple pathways potentially involved in metastatic invasion.Inhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin InteractionThe protein kinase 2 inhibitor tetrabromobenzotriazole protects against renal ischemia reperfusion injury.Simultaneous determination of wogonin, oroxylin a, schisandrin, paeoniflorin and emodin in rat serum by HPLC-MS/MS and application to pharmacokinetic studies.(E)-3-(3-methoxyphenyl)-1-(2-pyrrolyl)-2-propenone displays suppression of inflammatory responses via inhibition of Src, Syk, and NF-κB.Redundant synthesis of a conidial polyketide by two distinct secondary metabolite clusters in Aspergillus fumigatus.Berberine attenuates myocardial ischemia reperfusion injury by suppressing the activation of PI3K/AKT signalingExtract of Polygonum cuspidatum Attenuates Diabetic Retinopathy by Inhibiting the High-Mobility Group Box-1 (HMGB1) Signaling Pathway in Streptozotocin-Induced Diabetic Rats.Emodin potentiates the antiproliferative effect of interferon α/β by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasomeEmodin Bidirectionally Modulates Macrophage Polarization and Epigenetically Regulates Macrophage Memory.Efficacy and safety of Chinese herbal medicine for chronic prostatitis associated with damp-heat and blood-stasis syndromes: a meta-analysis and literature review.Emodin inhibits migration and invasion of MHCC-97H human hepatocellular carcinoma cells.Comparative proteomic analysis of liver antioxidant mechanisms in Megalobrama amblycephala stimulated with dietary emodin.Compounds from Chinese herbal medicines as reversal agents for P-glycoprotein-mediated multidrug resistance in tumours.Novel effects of the cyclooxygenase-2-selective inhibitor NS-398 on IL-1β-induced cyclooxygenase-2 and IL-8 expression in human ovarian granulosa cells.Emodin Inhibits Breast Cancer Growth by Blocking the Tumor-Promoting Feedforward Loop between Cancer Cells and Macrophages.β-Carotene Induces Apoptosis in Human Esophageal Squamous Cell Carcinoma Cell Lines via the Cav-1/AKT/NF-κB Signaling Pathway.Emodin and Its Role in Chronic Diseases.SZC017, a novel oleanolic acid derivative, induces apoptosis and autophagy in human breast cancer cells.Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics.Cyclometalated Ruthenium(II) Anthraquinone Complexes Exhibit Strong Anticancer Activity in Hypoxic Tumor Cells.TLR4-MyD88-TRAF6-TAK1 Complex-Mediated NF-κB Activation Contribute to the Anti-Inflammatory Effect of V8 in LPS-Induced Human Cervical Cancer SiHa Cells.Respiratory status determines the effect of emodin on cell viability.Effect of Emodin on Preventing Postoperative Intra-Abdominal Adhesion Formation.Emodin-loaded magnesium silicate hollow nanocarriers for anti-angiogenesis treatment through inhibiting VEGF.Emodin and rhein decrease levels of hypoxia-inducible factor-1α in human pancreatic cancer cells and attenuate cancer cachexia in athymic mice carrying these cells.Cytotoxic effects of the anthraquinone derivatives 1'-deoxyrhodoptilometrin and (S)-(-)-rhodoptilometrin isolated from the marine echinoderm Comanthus sp.Emodin, an anthraquinone derivative, protects against gamma radiation-induced toxicity by inhibiting DNA damage and oxidative stress.The Role of Resveratrol in Cancer Therapy.Monocytes and macrophages in flow: an ESCCA initiative on advanced analyses of monocyte lineage using flow cytometry.Use of Chinese Medicine Reduces the Development of Cervical Cancer from Pap Smear-Diagnosed Cervical Dysplasia: A Case-Control Study.
P2860
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P2860
Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer.
description
article científic
@ca
article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
Targeted abrogation of diverse ...... ammatory disorders and cancer.
@en
type
label
Targeted abrogation of diverse ...... ammatory disorders and cancer.
@en
prefLabel
Targeted abrogation of diverse ...... ammatory disorders and cancer.
@en
P2093
P1433
P1476
Targeted abrogation of diverse ...... lammatory disorders and cancer
@en
P2093
Alan Prem Kumar
Benny K H Tan
Deepti Shrimali
Jingwen Zhang
Kwang Seok Ahn
Muthu K Shanmugam
P304
P356
10.1016/J.CANLET.2013.08.023
P407
P50
P577
2013-08-17T00:00:00Z