Principal component analysis: a method for determining the essential dynamics of proteins.
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Markov state models provide insights into dynamic modulation of protein functionDifferential global structural changes in the core particle of yeast and mouse proteasome induced by ligand bindingThe impact of Thr91 mutation on c-Src resistance to UM-164: molecular dynamics study revealed a new opportunity for drug design.JED: a Java Essential Dynamics Program for comparative analysis of protein trajectories.Topological obstructions in the way of data-driven collective variables.Herpes simplex virus-2 genital tract shedding is not predictable over months or years in infected persons.The Interaction of FABP with Kapα.Conformational Sampling and Binding Site Assessment of Suppression of Tumorigenicity 2 EctodomainEarly Events in the Amyloid Formation of the A546T Mutant of Transforming Growth Factor β-Induced Protein in Corneal Dystrophies Compared to the Nonfibrillating R555W and R555Q MutantsPrediction and validation of protein intermediate states from structurally rich ensembles and coarse-grained simulations.Exploring the complete mutational space of the LDL receptor LA5 domain using molecular dynamics: linking SNPs with disease phenotypes in familial hypercholesterolemia.Specification of binding modes between a transmembrane peptide mimic of ATP6V0C and polytopic E5 of human papillomavirus-16.Charting molecular free-energy landscapes with an atlas of collective variables.Structural insights into the Middle East respiratory syndrome coronavirus 4a protein and its dsRNA binding mechanism.Structural variability of C3larvin toxin. Intrinsic dynamics of the α/β fold of the C3-like group of mono-ADP-ribosyltransferase toxins.A molecular dynamics simulation study decodes the early stage of the disassembly process abolishing the human SAMHD1 function.Double Mutants in DNA Gyrase Lead to Ofloxacin Resistance in Mycobacterium tuberculosis.On the analysis and comparison of conformer-specific essential dynamics upon ligand binding to a protein.Understanding Russell's viper venom factor V activator's substrate specificity by surface plasmon resonance and in-silico studies.Effects of Coarse Graining and Saturation of Hydrocarbon Chains on Structure and Dynamics of Simulated Lipid Molecules.Distant Phe345 mutation compromises the stability and activity of Mycobacterium tuberculosis isocitrate lyase by modulating its structural flexibility.Systematic Dissociation Pathway Searches Guided by Principal Component Modes.Structure and Dynamics of Cas9 HNH Domain Catalytic State.Detecting transitions in protein dynamics using a recurrence quantification analysis based bootstrap method.Emergence of a Promising Lead Compound in the Treatment of Triple Negative Breast Cancer: An Insight into Conformational Features and Ligand Binding Landscape of c-Src Protein with UM-164.Molecular dynamics simulations of the glucocorticoid receptor DNA-binding domain suggest a role of the lever-arm mobility in transcriptional output.Design of inhibitory peptide targeting Toxoplasma gondii RON4-human β-tubulin interactions by implementing structural bioinformatics methods.Structural insights into impact of Y134F mutation and discovery of novel fungicidal compounds against CYP51 in Puccinia triticina.Insights into the Effect of the G245S Single Point Mutation on the Structure of p53 and the Binding of the Protein to DNA.Structure prediction and functional analyses of a thermostable lipase obtained from Shewanella putrefaciens.Alanine mutation of the catalytic sites of Pantothenate Synthetase causes distinct conformational changes in the ATP binding region.Re-emergence of an orphan therapeutic target for the treatment of resistant prostate cancer - a thorough conformational and binding analysis for ROR-γ protein.New insights on repellent recognition by Anopheles gambiae odorant-binding protein 1.Dynamics of fluoroquinolones induced resistance in DNA gyrase of Mycobacterium tuberculosis.In Silico Studies of Small Molecule Interactions with Enzymes Reveal Aspects of Catalytic FunctionTwo distinct conformations of factor H regulate discrete complement-binding functions in the fluid phase and at cell surfacesMODE-TASK: large-scale protein motion tools
P2860
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P2860
Principal component analysis: a method for determining the essential dynamics of proteins.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Principal component analysis: ...... ssential dynamics of proteins.
@en
type
label
Principal component analysis: ...... ssential dynamics of proteins.
@en
prefLabel
Principal component analysis: ...... ssential dynamics of proteins.
@en
P2860
P1476
Principal component analysis: ...... ssential dynamics of proteins.
@en
P2093
Charles C David
Donald J Jacobs
P2860
P304
P356
10.1007/978-1-62703-658-0_11
P407
P577
2014-01-01T00:00:00Z