Resilient and resourceful: genome maintenance strategies in hematopoietic stem cells.
about
Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?Haematopoietic and immune defects associated with GATA2 mutation.Epigenetic changes mediated by polycomb repressive complex 2 and E2a are associated with drug resistance in a mouse model of lymphoma.Endogenous DNA Damage Leads to p53-Independent Deficits in Replicative Fitness in Fetal Murine Fancd2(-/-) Hematopoietic Stem and Progenitor Cells.Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons.Cooperation of imipramine blue and tyrosine kinase blockade demonstrates activity against chronic myeloid leukemia.Surviving change: the metabolic journey of hematopoietic stem cells.Normal and leukemic stem cell niches: insights and therapeutic opportunities.Kat3 coactivators in somatic stem cells and cancer stem cells: biological roles, evolution, and pharmacologic manipulation.Metabolic regulation of stem cell function in tissue homeostasis and organismal ageing.CD44 standard and CD44v10 isoform expression on leukemia cells distinctly influences niche embedding of hematopoietic stem cellsDNA-damage response in hematopoietic stem cells: an evolutionary trade-off between blood regeneration and leukemia suppression.CBP/Catenin antagonists: Targeting LSCs' Achilles heel.Integrin-linked kinase regulates the niche of quiescent epidermal stem cells.SMYD2 lysine methyltransferase regulates leukemia cell growth and regeneration after genotoxic stressRole of NOX2 for leukaemic expansion in a murine model of BCR-ABL1(+) leukaemia.Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors.Thrombopoietin protects hematopoietic stem cells from retrotransposon-mediated damage by promoting an antiviral response.Attenuated DNA damage responses and increased apoptosis characterize human hematopoietic stem cells exposed to irradiation.
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P2860
Resilient and resourceful: genome maintenance strategies in hematopoietic stem cells.
description
article científic
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article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Resilient and resourceful: genome maintenance strategies in hematopoietic stem cells.
@en
type
label
Resilient and resourceful: genome maintenance strategies in hematopoietic stem cells.
@en
prefLabel
Resilient and resourceful: genome maintenance strategies in hematopoietic stem cells.
@en
P2860
P1476
Resilient and resourceful: genome maintenance strategies in hematopoietic stem cells
@en
P2093
Sietske T Bakker
P2860
P304
P356
10.1016/J.EXPHEM.2013.09.007
P577
2013-09-22T00:00:00Z