Normal and leukemic stem cell niches: insights and therapeutic opportunities.
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Mesenchymal Stem and Progenitor Cells in Normal and Dysplastic Hematopoiesis-Masters of Survival and Clonality?Hypoxia and Hypoxia-Inducible Factors in LeukemiasThe Hematopoietic Niche in Myeloproliferative NeoplasmsCytokine Regulation of Microenvironmental Cells in Myeloproliferative NeoplasmsBone Marrow Blood Vessels: Normal and Neoplastic NicheUpdate on acute myeloid leukemia stem cells: New discoveries and therapeutic opportunitiesCommunication of bone cells with hematopoiesis, immunity and energy metabolismApplication of single-cell genomics in cancer: promise and challengesAn artificial niche preserves the quiescence of muscle stem cells and enhances their therapeutic efficacy.Latexin Inactivation Enhances Survival and Long-Term Engraftment of Hematopoietic Stem Cells and Expands the Entire Hematopoietic System in Mice.HDAC8 overexpression in mesenchymal stromal cells from JAK2+ myeloproliferative neoplasms: a new therapeutic target?An abnormal bone marrow microenvironment contributes to hematopoietic dysfunction in Fanconi anemia.Detailed Characterization of Mesenchymal Stem/Stromal Cells from a Large Cohort of AML Patients Demonstrates a Definitive Link to Treatment Outcomes.Molecular Checkpoint Decisions Made by Subverted Vascular Niche Transform Indolent Tumor Cells into Chemoresistant Cancer Stem CellsNiche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation.Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion.A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells.Niche signaling promotes stem cell survival in the Drosophila testis via the JAK-STAT target DIAP1Insulin-InsR signaling drives multipotent progenitor differentiation toward lymphoid lineages.Core Circadian Clock Genes Regulate Leukemia Stem Cells in AMLChronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewalUtilizing cell-based therapeutics to overcome immune evasion in hematologic malignancies.Human mesenchymal stromal/stem cells acquire immunostimulatory capacity upon cross-talk with natural killer cells and might improve the NK cell function of immunocompromised patients.Targeted positron emission tomography imaging of CXCR4 expression in patients with acute myeloid leukemiaCooperation of imipramine blue and tyrosine kinase blockade demonstrates activity against chronic myeloid leukemia.The Role of the Bone Marrow Stromal Compartment in the Hematopoietic Response to Microbial Infections.Understanding of leukemic stem cells and their clinical implications.Clonal evolution of acute myeloid leukemia highlighted by latest genome sequencing studies.Sensitizing leukemia stem cells to NF-κB inhibitor treatment in vivo by inactivation of both TNF and IL-1 signaling.Mechanism and Function of Angiogenin in Hematopoietic Malignancy.Concise Review: MSC-Derived Exosomes for Cell-Free Therapy.Regulation of hematopoietic stem cells in the niche.Unraveling mechanisms of mesenchymal stromal cell-mediated immunomodulation through patient monitoring and product characterization.The human and murine hematopoietic stem cell niches: are they comparable?Therapeutically targeting SELF-reinforcing leukemic niches in acute myeloid leukemia: A worthy endeavor?Small-molecule Hedgehog inhibitor attenuates the leukemia-initiation potential of acute myeloid leukemia cells.On the potential role of DNMT1 in acute myeloid leukemia and myelodysplastic syndromes: not another mutated epigenetic driver.Endothelial-to-hematopoietic transition: Notch-ing vessels into blood.Leptin-receptor-expressing bone marrow stromal cells are myofibroblasts in primary myelofibrosis.The functional interplay between systemic cancer and the hematopoietic stem cell niche.
P2860
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P2860
Normal and leukemic stem cell niches: insights and therapeutic opportunities.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Normal and leukemic stem cell niches: insights and therapeutic opportunities.
@en
type
label
Normal and leukemic stem cell niches: insights and therapeutic opportunities.
@en
prefLabel
Normal and leukemic stem cell niches: insights and therapeutic opportunities.
@en
P2860
P1433
P1476
Normal and leukemic stem cell niches: insights and therapeutic opportunities
@en
P2093
Timothy B Campbell
P2860
P304
P356
10.1016/J.STEM.2015.02.014
P407
P577
2015-03-01T00:00:00Z