How should we define STAT3 as an oncogene and as a potential target for therapy?

How should we define STAT3 as an oncogene and as a potential target for therapy?

Item
http://www.wikidata.org/entity/Q38143961
Galiellalactone is a direct inhibitor of the transcription factor STAT3 in prostate cancer cellsUpregulation of TPX2 by STAT3: identification of a novel STAT3 binding site.A novel small molecule STAT3 inhibitor, LY5, inhibits cell viability, colony formation, and migration of colon and liver cancer cells.MicroRNA-424 impairs ubiquitination to activate STAT3 and promote prostate tumor progression.CD44 and CD24 coordinate the reprogramming of nasopharyngeal carcinoma cells towards a cancer stem cell phenotype through STAT3 activation.STAT3 in Cancer-Friend or Foe?STAT3 as a possible therapeutic target in human malignancies: lessons from acute myeloid leukemia.JAK inhibition and progressive kidney disease.Epstein-Barr Virus Latent Membrane Protein 2A (LMP2A) enhances IL-10 production through the activation of Bruton's tyrosine kinase and STAT3.An IL-27/Stat3 axis induces expression of programmed cell death 1 ligands (PD-L1/2) on infiltrating macrophages in lymphoma.Irinotecan treatment and senescence failure promote the emergence of more transformed and invasive cells that depend on anti-apoptotic Mcl-1.Resistance of Cancer Cells to Targeted Therapies Through the Activation of Compensating Signaling Loops.Isocryptotanshinone, a STAT3 inhibitor, induces apoptosis and pro-death autophagy in A549 lung cancer cells.Characterisation of HRas local signal transduction networks using engineered site-specific exchange factors.
P2860

How should we define STAT3 as an oncogene and as a potential target for therapy?

Item
http://www.wikidata.org/entity/Q38143961
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
How should we define STAT3 as an oncogene and as a potential target for therapy?
@en
type
label
How should we define STAT3 as an oncogene and as a potential target for therapy?
@en
prefLabel
How should we define STAT3 as an oncogene and as a potential target for therapy?
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
How should we define STAT3 as an oncogene and as a potential target for therapy?
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932