The chemistry and biology of the immunomodulating agent gliotoxin and related epipolythiodioxopiperazines.
about
Epidithiodioxopiperazines. occurrence, synthesis and biogenesisThe mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in miceEnantioselective total synthesis of plectosphaeroic acid BEnantioselective total syntheses of plectosphaeroic acids B and C.Optimization and mechanistic studies of psammaplin A type antibacterial agents active against methicillin-resistant Staphylococcus aureus (MRSA).Identification of small-molecule inhibitors of ricin and shiga toxin using a cell-based high-throughput screenEnantioselective Synthesis of (-)-Acetylapoaranotin.Detection of gliotoxin in experimental and human aspergillosisFungal metabolite gliotoxin targets flavocytochrome b558 in the activation of the human neutrophil NADPH oxidaseRedox sensitive epidithiodioxopiperazines in biological mechanisms of toxicity.Fungal metabolite gliotoxin inhibits assembly of the human respiratory burst NADPH oxidaseSynthesis and Anticancer Activity of Epipolythiodiketopiperazine AlkaloidsEnantioselective total synthesis of (+)-gliocladine C: convergent construction of cyclotryptamine-fused polyoxopiperazines and a general approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors.Tricyclic Analogues of Epidithiodioxopiperazine Alkaloids with Promising In Vitro and In Vivo Antitumor Activity.The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB.Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G, 8,8'-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haGeneral approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors: enantioselective total syntheses of (+)- and (-)-gliocladine C, (+)-leptosin D, (+)-T988C, (+)-bionectin A, and (+)-gliocladin A.Concise Total Synthesis of (+)-Bionectins A and C.Gliotoxin causes apoptosis and necrosis of rat Kupffer cells in vitro and in vivo in the absence of oxidative stress: exacerbation by caspase and serine protease inhibition.Aspergillosis and stem cell transplantation: An overview of experimental pathogenesis studies.A brief history of antibiotics and select advances in their synthesis.A novel redox mechanism for the glutathione-dependent reversible uptake of a fungal toxin in cells.Frequency and species distribution of gliotoxin-producing Aspergillus isolates recovered from patients at a tertiary-care cancer centerConcise Total Synthesis of (+)-Gliocladins B and CHow to improve the hygienic quality of forages for horse feeding.Influx of calcium through a redox-sensitive plasma membrane channel in thymocytes causes early necrotic cell death induced by the epipolythiodioxopiperazine toxins.Effect and stability of gliotoxin, an Aspergillus fumigatus toxin, on in vitro rumen fermentation.Stereoselective construction of a key hydroindole precursor of epidithiodiketopiperazine (ETP) natural products.A Unified Strategy to 6-5-6-5-6-Membered Epipolythiodiketopiperazines: Studies towards the Total Synthesis of Scabrosin Diacetate and Haematocin.
P2860
Q26849609-FBCC8CE5-DCD4-4EEC-9CCB-5CF5BE57195CQ28511677-F5A9FD3B-7FDA-494E-8DAA-CEE8D26FAC21Q30538149-EED96511-D59B-47B8-BCDB-91F9C83AD44AQ30556998-3FD2AED7-8185-4266-95A7-672B333ED8D3Q32025736-E54E8738-C398-4779-8DB8-BB5D9490BB36Q33547235-94901DF2-5896-4231-A495-38D36FB0F7ECQ33551573-99C9F803-E6C9-4207-BF2F-93A92ECB6BD0Q33557456-55BB068E-FC7B-4A65-AF0C-922B68F091A4Q33558138-4D802196-8251-4E6F-84E5-0DE78FC17C17Q34122729-3E708D44-3EC4-4E4B-B772-AFA7DAA9D8B8Q34146538-DC99D95F-0158-4504-BFEC-5DAC86295933Q34361796-A339EF66-C3E8-4C93-A059-3EA96B198523Q34953920-205F8710-2CCB-468F-AA4B-1CD6BCF263CAQ35753464-D5BB4DA8-2432-4C01-B713-E9C420188CE1Q36366520-F4B8AE68-2D62-4C07-A2F3-F300BAA241D0Q36376066-438AC976-84EC-4E48-9F4B-A6B195129D50Q36807311-C53EBA73-10E3-49FA-A868-32D25BCA6B97Q37020407-20608F02-F80A-49EE-AB6F-11449D32BFABQ37394545-1F057944-FE1A-4D57-9D05-3C0B496402AEQ38968506-608B9D38-7594-4809-8FA1-C422D04F9217Q39414195-6631FCF9-AFCA-4ECD-B07D-1701119A3269Q40639199-3885EC6D-4E3C-4D56-B43C-AA62F933352CQ40709787-73F81344-5671-43F5-83C5-24D99DEC0CE0Q41974936-9AACA304-6072-430E-ADA1-77BDCA4A6ADEQ43709264-6D7D9A0C-F47A-426D-8C36-763C7F4FFEA8Q44026925-69839E75-94CE-48C1-A3D8-42569E57D629Q45235759-6B7A182E-4679-4A85-A6D2-D91519DF7372Q50453162-55708DDB-9A3A-4F62-B7C5-28F31E869829Q50954298-BCED0596-D265-4173-AD86-EE4D122449DE
P2860
The chemistry and biology of the immunomodulating agent gliotoxin and related epipolythiodioxopiperazines.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
The chemistry and biology of t ...... d epipolythiodioxopiperazines.
@en
type
label
The chemistry and biology of t ...... d epipolythiodioxopiperazines.
@en
prefLabel
The chemistry and biology of t ...... d epipolythiodioxopiperazines.
@en
P2093
P2860
P356
P1476
The chemistry and biology of t ...... d epipolythiodioxopiperazines.
@en
P2093
Eichner RD
Müllbacher A
P2860
P304
P356
10.1002/MED.2610080404
P577
1988-10-01T00:00:00Z