Higher order structure characterization of protein therapeutics by hydrogen/deuterium exchange mass spectrometry.
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Novel Structural Approaches to Study GPCR RegulationDiscovery and Characterization of Phage Display-Derived Human Monoclonal Antibodies against RSV F GlycoproteinChanges in protein structure monitored by use of gas-phase hydrogen/deuterium exchangeHydrogen-deuterium exchange mass spectrometry for determining protein structural changes in drug discovery.Coarse-Grained Conformational Sampling of Protein Structure Improves the Fit to Experimental Hydrogen-Exchange Data.Optimization and application of atmospheric pressure chemical and photoionization hydrogen-deuterium exchange mass spectrometry for speciation of oxygen-containing compounds.MEMHDX: an interactive tool to expedite the statistical validation and visualization of large HDX-MS datasets.HDX-MS guided drug discovery: small molecules and biopharmaceuticals.Molecular and functional analysis of monoclonal antibodies in support of biologics development.Characterization of Aggregation Propensity of a Human Fc-Fusion Protein Therapeutic by Hydrogen/Deuterium Exchange Mass Spectrometry.Mapping insulin non-covalent interactions with natural polysaccharides by hydrogen/deuterium exchange mass spectrometry.Computationally-driven identification of antibody epitopes.Orthogonal Mass Spectrometry-Based Footprinting for Epitope Mapping and Structural Characterization: The IL-6 Receptor upon Binding of Protein Therapeutics.Hydrogen/deuterium exchange mass spectrometry and computational modeling reveal a discontinuous epitope of an antibody/TL1A Interaction.Monoclonal antibody higher order structure analysis by high throughput protein conformational array.A Retrospective Evaluation of the Use of Mass Spectrometry in FDA Biologics License Applications.Localized conformational interrogation of antibody and antibody-drug conjugates by site-specific carboxyl group footprinting.
P2860
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P2860
Higher order structure characterization of protein therapeutics by hydrogen/deuterium exchange mass spectrometry.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Higher order structure charact ...... um exchange mass spectrometry.
@en
type
label
Higher order structure charact ...... um exchange mass spectrometry.
@en
prefLabel
Higher order structure charact ...... um exchange mass spectrometry.
@en
P2860
P1476
Higher order structure charact ...... ium exchange mass spectrometry
@en
P2093
Guodong Chen
P2860
P2888
P304
P356
10.1007/S00216-014-7924-3
P407
P577
2014-06-20T00:00:00Z