Targeting core (mutated) pathways of high-grade gliomas: challenges of intrinsic resistance and drug efflux.
about
Angiopep-2-conjugated poly(ethylene glycol)-co- poly(ε-caprolactone) polymersomes for dual-targeting drug delivery to glioma in rats.ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclib.Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8.
P2860
Targeting core (mutated) pathways of high-grade gliomas: challenges of intrinsic resistance and drug efflux.
description
2013 nî lūn-bûn
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2013年の論文
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name
Targeting core (mutated) pathw ...... ic resistance and drug efflux.
@en
type
label
Targeting core (mutated) pathw ...... ic resistance and drug efflux.
@en
prefLabel
Targeting core (mutated) pathw ...... ic resistance and drug efflux.
@en
P2093
P2860
P356
P1433
P1476
Targeting core (mutated) pathw ...... sic resistance and drug efflux
@en
P2093
Diana Hanekamp
Dieta Brandsma
Jos H Beijnen
Olaf van Tellingen
P2860
P304
P356
10.2217/CNS.13.15
P577
2013-05-01T00:00:00Z