Shark variable new antigen receptor biologics - a novel technology platform for therapeutic drug development.
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An update on antibody-based immunotherapies for Clostridium difficile infectionFish ImmunoglobulinsPeptide aptamers: development and applications.Importance of Hypervariable Region 2 for Stability and Affinity of a Shark Single-Domain Antibody Specific for Ebola Virus NucleoproteinA simplified procedure for antibody engineering by yeast surface display: Coupling display levels and target binding by ribosomal skipping.Structural insights and biomedical potential of IgNAR scaffolds from sharks.Single-domain antibodies for biomedical applications.Semi-synthetic vNAR libraries screened against therapeutic antibodies primarily deliver anti-idiotypic binders.Therapeutic Potential of Shark Anti-ICOSL VNAR Domains is Exemplified in a Murine Model of Autoimmune Non-Infectious Uveitis.In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development.Single Domain Antibodies as New Biomarker Detectors.A Novel Affinity Tag, ABTAG, and Its Application to the Affinity Screening of Single-Domain Antibodies Selected by Phage Display.Generation of Semi-Synthetic Shark IgNAR Single-Domain Antibody Libraries.Intraocular Penetration of a vNAR: In Vivo and In Vitro VEGF165 Neutralization.In silico-designed mutations increase variable new-antigen receptor single-domain antibodies for VEGF165 neutralization.Anti-ICOSL New Antigen Receptor Domains Inhibit T Cell Proliferation and Reduce the Development of Inflammation in the Collagen-Induced Mouse Model of Rheumatoid Arthritis
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P2860
Shark variable new antigen receptor biologics - a novel technology platform for therapeutic drug development.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Shark variable new antigen rec ...... therapeutic drug development.
@en
type
label
Shark variable new antigen rec ...... therapeutic drug development.
@en
prefLabel
Shark variable new antigen rec ...... therapeutic drug development.
@en
P2093
P2860
P1476
Shark variable new antigen rec ...... therapeutic drug development.
@en
P2093
Andrew Porter
Caroline Barelle
John Steven
Laura Ferguson
Marina Kovaleva
P2860
P304
P356
10.1517/14712598.2014.937701
P407
P577
2014-08-04T00:00:00Z