Toward selective TYK2 inhibitors as therapeutic agents for the treatment of inflammatory diseases.

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In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity

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Toward selective TYK2 inhibitors as therapeutic agents for the treatment of inflammatory diseases.

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2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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2014年论文

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2014年论文

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name

Toward selective TYK2 inhibito ...... ment of inflammatory diseases.

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Toward selective TYK2 inhibito ...... ment of inflammatory diseases.

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Toward selective TYK2 inhibito ...... ment of inflammatory diseases.

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P1476

Toward selective TYK2 inhibito ...... ment of inflammatory diseases.

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P2093

Christel J Menet

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P2860

Discovery of potent and selective pyrazolopyrimidine janus kinase 2 inhibitors

Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris

Identification of C-2 hydroxyethyl imidazopyrrolopyridines as potent JAK1 inhibitors with favorable physicochemical properties and high selectivity over JAK2

Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2

Fragment-based discovery of JAK-2 inhibitors

Identification of imidazo-pyrrolopyridines as novel and potent JAK1 inhibitors

Lead optimization of a 4-aminopyridine benzamide scaffold to identify potent, selective, and orally bioavailable TYK2 inhibitors

Lead identification of novel and selective TYK2 inhibitors

2-Amino-[1,2,4]triazolo[1,5-a]pyridines as JAK2 inhibitors

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

P304

449-466

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scholarly article

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10.4155/PPA.14.23

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2014-07-01T00:00:00Z

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25291316

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Toward selective TYK2 inhibitors as therapeutic agents for the treatment of inflammatory diseases.

about

P2860

P2860

Toward selective TYK2 inhibitors as therapeutic agents for the treatment of inflammatory diseases.

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P1476

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