Transforming growth factor-beta-stimulated endocardial cell transformation is dependent on Par6c regulation of RhoA.
about
Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progressionSignaling via the Tgf-beta type I receptor Alk5 in heart developmentThe chick embryo as an expanding experimental model for cancer and cardiovascular researchHPV16 E7-dependent transformation activates NHE1 through a PKA-RhoA-induced inhibition of p38alpha.BMP-2 and TGFβ2 shared pathways regulate endocardial cell transformation.Interaction between FIP5 and SNX18 regulates epithelial lumen formationTGFβ and BMP-2 regulate epicardial cell invasion via TGFβR3 activation of the Par6/Smurf1/RhoA pathway.BMP2 signals loss of epithelial character in epicardial cells but requires the Type III TGFβ receptor to promote invasion.Atrioventricular valve development: new perspectives on an old theme.Common pathways regulate Type III TGFβ receptor-dependent cell invasion in epicardial and endocardial cells.Role of TGF-β and the tumor microenvironment during mammary tumorigenesisPar complex in cancer: a regulator of normal cell polarity joins the dark side.SMURF1 plays a role in EGF-induced breast cancer cell migration and invasion.Altered ubiquitin-proteasome signaling in right ventricular hypertrophy and failureRedundant functions of I-BAR family members, IRSp53 and IRTKS, are essential for embryonic development.What chick and mouse models have taught us about the role of the endocardium in congenital heart disease.Epithelial cell polarity, stem cells and cancer.Collagen gel analysis of epithelial-mesenchymal transition in the embryo heart: an in vitro model system for the analysis of tissue interaction, signal transduction, and environmental effects.A Smurf1 tale: function and regulation of an ubiquitin ligase in multiple cellular networks.Snail homolog 1 is involved in epithelial-mesenchymal transition-like processes in human glioblastoma cells.The role of small GTPases of the Rho/Rac family in TGF-β-induced EMT and cell motility in cancer.Endocardial cell epithelial-mesenchymal transformation requires Type III TGFβ receptor interaction with GIPC.Spatial transcriptional profile of the chick and mouse endocardial cushions identify novel regulators of endocardial EMT in vitro.Type III TGFβ receptor and Src direct hyaluronan-mediated invasive cell motility.Myeloid cells: Prime drivers of tumor progression.Whole exome sequencing in 342 congenital cardiac left sided lesion cases reveals extensive genetic heterogeneity and complex inheritance patterns.Mechanotransduction Mechanisms in Mitral Valve Physiology and Disease Pathogenesis.Regulation of spermatid polarity by the actin- and microtubule (MT)-based cytoskeletons.The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development.
P2860
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P2860
Transforming growth factor-beta-stimulated endocardial cell transformation is dependent on Par6c regulation of RhoA.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Transforming growth factor-bet ...... t on Par6c regulation of RhoA.
@en
type
label
Transforming growth factor-bet ...... t on Par6c regulation of RhoA.
@en
prefLabel
Transforming growth factor-bet ...... t on Par6c regulation of RhoA.
@en
P2093
P2860
P356
P1476
Transforming growth factor-bet ...... t on Par6c regulation of RhoA.
@en
P2093
George E Davis
Jeffrey L Wrana
Joey V Barnett
Todd A Townsend
P2860
P304
13834-13841
P356
10.1074/JBC.M710607200
P407
P577
2008-03-14T00:00:00Z