Desaturation and hydroxylation. Residues 148 and 324 of Arabidopsis FAD2, in addition to substrate chain length, exert a major influence in partitioning of catalytic specificity.
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Biosynthesis and function of polyacetylenes and allied natural productsLinking enzyme sequence to function using Conserved Property Difference Locator to identify and annotate positions likely to control specific functionalityCoexpressing Escherichia coli cyclopropane synthase with Sterculia foetida Lysophosphatidic acid acyltransferase enhances cyclopropane fatty acid accumulationHigher plant cytochrome b5 polypeptides modulate fatty acid desaturationComparative analysis of fatty acid desaturases in cyanobacterial genomesHuman cytochrome P450 27C1 catalyzes 3,4-desaturation of retinoids.Atypical biosynthetic properties of a Delta 12/nu+3 desaturase from the model basidiomycete Phanerochaete chrysosporium.Molecular analysis of a bifunctional fatty acid conjugase/desaturase from tung. Implications for the evolution of plant fatty acid diversity.Characterization and analysis of the cotton cyclopropane fatty acid synthase family and their contribution to cyclopropane fatty acid synthesisManganese catalysts for C-H activation: an experimental/theoretical study identifies the stereoelectronic factor that controls the switch between hydroxylation and desaturation pathways.Elucidation of the pathway to astaxanthin in the flowers of Adonis aestivalis.Functional diversity in fungal fatty acid synthesis: the first acetylenase from the Pacific golden chanterelle, Cantharellus formosus.Dihydroceramide-based response to hypoxia.Genome-wide analysis of the omega-3 fatty acid desaturase gene family in GossypiumIdentification of bifunctional delta12/omega3 fatty acid desaturases for improving the ratio of omega3 to omega6 fatty acids in microbes and plants.Δ12-Fatty acid desaturase from Candida parapsilosis is a multifunctional desaturase producing a range of polyunsaturated and hydroxylated fatty acidsDeciphering gamma-decalactone biosynthesis in strawberry fruit using a combination of genetic mapping, RNA-Seq and eQTL analysesExpanding the enzyme universe: accessing non-natural reactions by mechanism-guided directed evolution.Conjugated fatty acid synthesis: residues 111 and 115 influence product partitioning of Momordica charantia conjugaseParallel and competitive pathways for substrate desaturation, hydroxylation, and radical rearrangement by the non-heme diiron hydroxylase AlkB.Switching desaturase enzyme specificity by alternate subcellular targeting.Revealing the catalytic potential of an acyl-ACP desaturase: tandem selective oxidation of saturated fatty acids.Desaturases: emerging models for understanding functional diversification of diiron-containing enzymes.Metabolic engineering of plant oils and waxes for use as industrial feedstocks.The Need for Integrated Approaches in Metabolic Engineering.Identification of multiple lipid genes with modifications in expression and sequence associated with the evolution of hydroxy fatty acid accumulation in Physaria fendleri.Divergent mechanisms of iron-containing enzymes for hydrocarbon biosynthesis.Mechanistic and structural insights into the regioselectivity of an acyl-CoA fatty acid desaturase via directed molecular evolutionDiversity of Δ12 fatty acid desaturases in santalaceae and their role in production of seed oil acetylenic fatty acids.Domain swapping localizes the structural determinants of regioselectivity in membrane-bound fatty acid desaturases of Caenorhabditis elegans.Molecular recognition in Mn-catalyzed C-H oxidation. Reaction mechanism and origin of selectivity from a DFT perspective.Genetic variation of six desaturase genes in flax and their impact on fatty acid composition.Mechanism of 1,4-dehydrogenation catalyzed by a fatty acid (1,4)-desaturase of Calendula officinalis.Evidence linking the Pseudomonas oleovorans alkane omega-hydroxylase, an integral membrane diiron enzyme, and the fatty acid desaturase family.Stereochemistry of a bifunctional dihydroceramide delta 4-desaturase/hydroxylase from Candida albicans; a key enzyme of sphingolipid metabolism.Dimorphecolic acid is synthesized by the coordinate activities of two divergent Delta12-oleic acid desaturases.Quantitative deuterium isotopic profiling at natural abundance indicates mechanistic differences for delta 12-epoxidase and delta 12-desaturase in Vernonia galamensis.An oleate hydroxylase from the fungus Claviceps purpurea: cloning, functional analysis, and expression in Arabidopsis.The FAD2 Gene in Plants: Occurrence, Regulation, and Role.Identification of bottlenecks in the accumulation of cyclic fatty acids in camelina seed oil.
P2860
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P2860
Desaturation and hydroxylation. Residues 148 and 324 of Arabidopsis FAD2, in addition to substrate chain length, exert a major influence in partitioning of catalytic specificity.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Desaturation and hydroxylation ...... ning of catalytic specificity.
@en
type
label
Desaturation and hydroxylation ...... ning of catalytic specificity.
@en
prefLabel
Desaturation and hydroxylation ...... ning of catalytic specificity.
@en
P2093
P2860
P356
P1476
Desaturation and hydroxylation ...... ning of catalytic specificity.
@en
P2093
Edward Whittle
John A Broadwater
John Shanklin
P2860
P304
15613-15620
P356
10.1074/JBC.M200231200
P407
P577
2002-02-25T00:00:00Z