N- and O-linked keratan sulfate on the hyaluronan binding region of aggrecan from mature and immature bovine cartilage.
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Keratan sulfate biosynthesisDeterminants of Glycosaminoglycan (GAG) StructureMembrane-type 1 MMP (MMP-14) cleaves at three sites in the aggrecan interglobular domainIdentification of hyaluronan-binding domains of aggrecanAggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro.Eosinophil cationic protein (ECP): molecular and biological properties and the use of ECP as a marker of eosinophil activation in disease.Metabolism of cartilage proteoglycans in health and diseaseGranules of human eosinophilic leucocytes and their mobilization.The functional heterogeneity of eosinophil cationic protein is determined by a gene polymorphism and post-translational modifications.Whole-genome sequencing of the snub-nosed monkey provides insights into folivory and evolutionary history.Induction of arthritis in BALB/c mice by cartilage link protein: involvement of distinct regions recognized by T and B lymphocytesThe role of aggrecan in normal and osteoarthritic cartilage.Extracellular superoxide dismutase inhibits inflammation by preventing oxidative fragmentation of hyaluronanPost-translational modifications in cartilage oligomeric matrix protein. Characterization of the N-linked oligosaccharides by matrix-assisted laser desorption ionization time-of-flight mass spectrometry.Conserved sequence in the aggrecan interglobular domain modulates cleavage by ADAMTS-4 and ADAMTS-5.Immunity to the G1 globular domain of the cartilage proteoglycan aggrecan can induce inflammatory erosive polyarthritis and spondylitis in BALB/c mice but immunity to G1 is inhibited by covalently bound keratan sulfate in vitro and in vivoAggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent.Arthritis induced by proteoglycan aggrecan G1 domain in BALB/c mice. Evidence for t cell involvement and the immunosuppressive influence of keratan sulfate on recognition of t and b cell epitopes.From housekeeper to microsurgeon: the diagnostic and therapeutic potential of ribonucleases.Role of unique basic residues in cytotoxic, antibacterial and antiparasitic activities of human eosinophil cationic protein.Respiratory syncytical virus-induced chemokine expression in the lower airways: eosinophil recruitment and degranulation.Variations in aggrecan structure modulate its susceptibility to aggrecanases.Hyaluronate degradation as an alternative mechanism for proteoglycan release from cartilage during interleukin-1beta-stimulated catabolism.A nonspecific, single-stranded nuclease activity with characteristics of a topoisomerase found in a major grass pollen allergen: possible biological significance.Aggrecan degradation in human intervertebral disc and articular cartilage.Tissue distribution and measurement of cartilage oligomeric matrix protein in patients with magnetic resonance imaging-detected bone bruises after acute anterior cruciate ligament tears.Rapid evolution of a unique family of primate ribonuclease genes.The characterization of versican and its message in human articular cartilage and intervertebral disc.N-linked keratan sulfate in the aggrecan interglobular domain potentiates aggrecanase activity.Ribonucleases as a host-defence family: evidence of evolutionarily conserved antimicrobial activity at the N-terminus.Keratan Sulphate, a complex Glycosaminoglycan with Unique Functional Capability.Cellular immunity to the G1 domain of cartilage proteoglycan aggrecan is enhanced in patients with rheumatoid arthritis but only after removal of keratan sulfate.Aggrecanase cleavage in juvenile idiopathic arthritis patients is minimally detected in the aggrecan interglobular domain but robust at the aggrecan C-terminus.Investigating ADAMTS-mediated aggrecanolysis in mouse cartilage.Generation and novel distribution of matrix metalloproteinase-derived aggrecan fragments in porcine cartilage explants.
P2860
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P2860
N- and O-linked keratan sulfate on the hyaluronan binding region of aggrecan from mature and immature bovine cartilage.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
N- and O-linked keratan sulfat ...... and immature bovine cartilage.
@en
type
label
N- and O-linked keratan sulfat ...... and immature bovine cartilage.
@en
prefLabel
N- and O-linked keratan sulfat ...... and immature bovine cartilage.
@en
P2093
P2860
P356
P1476
N- and O-linked keratan sulfat ...... and immature bovine cartilage.
@en
P2093
P2860
P304
20516-20524
P356
10.1074/JBC.270.35.20516
P407
P577
1995-09-01T00:00:00Z