6-mercaptopurine and 9-(2-phosphonyl-methoxyethyl) adenine (PMEA) transport altered by two missense mutations in the drug transporter gene ABCC4.

6-mercaptopurine and 9-(2-phosphonyl-methoxyethyl) adenine (PMEA) transport altered by two missense mutations in the drug transporter gene ABCC4.

Item
http://www.wikidata.org/entity/Q38293233
Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice.The Promise of Pharmacogenomics in Reducing Toxicity During Acute Lymphoblastic Leukemia Maintenance Treatment.Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes.Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains.Crucial role for phylogenetically conserved cytoplasmic loop 3 in ABCC4 protein expressionDrug transporter pharmacogenetics in nucleoside-based therapies.Pharmacogenetics of drug transporters in the enterohepatic circulation.Pharmacogenetic determinants of mercaptopurine disposition in children with acute lymphoblastic leukemia.Phase 0 and phase III transport in various organs: combined concept of phases in xenobiotic transport and metabolism.Liquid oral suspension adefovir dipivoxil (GS-02-526): an update on treatments for hepatitis B infection.Genetic variants in 6-mercaptopurine pathway as potential factors of hematological toxicity in acute lymphoblastic leukemia patients.ABCC4/MRP4: a MYCN-regulated transporter and potential therapeutic target in neuroblastoma.Quantitative Evaluation of Drug Resistance Profile of Cells Expressing Wild-Type or Genetic Polymorphic Variants of the Human ABC Transporter ABCC4.ABCC11/MRP8 polymorphisms affect 5-fluorouracil-induced severe toxicity and hepatic expression.Detoxification of ivermectin by ATP binding cassette transporter C4 and cytochrome P450 monooxygenase 6CJ1 in the human body louse, Pediculus humanus humanus.Revisiting the Role of Thiopurines in Inflammatory Bowel Disease Through Pharmacogenomics and Use of Novel Methods for Therapeutic Drug MonitoringABCC4 Variants Modify Susceptibility to Kawasaki Disease in a Southern Chinese Population
P2860

6-mercaptopurine and 9-(2-phosphonyl-methoxyethyl) adenine (PMEA) transport altered by two missense mutations in the drug transporter gene ABCC4.

Item
http://www.wikidata.org/entity/Q38293233
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
6-mercaptopurine and 9-(2-phos ...... e drug transporter gene ABCC4.
@en
type
label
6-mercaptopurine and 9-(2-phos ...... e drug transporter gene ABCC4.
@en
prefLabel
6-mercaptopurine and 9-(2-phos ...... e drug transporter gene ABCC4.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P356
P1433
P1476
6-mercaptopurine and 9-(2-phos ...... e drug transporter gene ABCC4.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698