The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage
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Role of MRP4 (ABCC4) in platelet adenine nucleotide-storage: evidence from patients with delta-storage pool deficienciesMultidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferationSphingosine-1-Phosphate and Its Receptors: A Mutual Link between Blood Coagulation and InflammationNew perspectives in signaling mediated by receptors coupled to stimulatory G protein: the emerging significance of cAMP efflux and extracellular cAMP-adenosine pathwayAssociation study of genetic polymorphism in ABCC4 with cyclophosphamide-induced adverse drug reactions in breast cancer patientsABC Transport Proteins in Cardiovascular Disease-A Brief Summary.SLC35D3 delivery from megakaryocyte early endosomes is required for platelet dense granule biogenesis and is differentially defective in Hermansky-Pudlak syndrome models.A mechanism of intracellular P2X receptor activation.Qualitative disorders of platelets and megakaryocytes.Novel Mutation in Bernard-Soulier Syndrome.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.Measurement and Clinical Significance of Biomarkers of Oxidative Stress in Humans.cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action.Hermansky-Pudlak syndrome: a disease of protein trafficking and organelle function.Defective release of α granule and lysosome contents from platelets in mouse Hermansky-Pudlak syndrome models.Activated platelets release sphingosine 1-phosphate and induce hypersensitivity to noxious heat stimuli in vivo.Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle.Sources, metabolism, and regulation of circulating sphingosine-1-phosphateImpaired platelet activation and cAMP homeostasis in MRP4-deficient mice.The ABCC4 membrane transporter modulates platelet aggregation.Role of the Caenorhabditis elegans multidrug resistance gene, mrp-4, in gut granule differentiationFunction and regulation of multidrug resistance proteins (MRPs) in the renal elimination of organic anions.Mechanism of platelet dense granule biogenesis: study of cargo transport and function of Rab32 and Rab38 in a model system.Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci.ABC drug transporters and immunity: novel therapeutic targets in autoimmunity and cancer.Advances in monitoring of aspirin therapy.Molecular determinants of platelet delta storage pool deficiencies: an update.Importance of ABCC1 for cancer therapy and prognosis.Minireview: SLCO and ABC transporters: a role for steroid transport in prostate cancer progression.6-mercaptopurine and 9-(2-phosphonyl-methoxyethyl) adenine (PMEA) transport altered by two missense mutations in the drug transporter gene ABCC4.Storage pool diseases illuminate platelet dense granule biogenesis.Vesicular nucleotide transporter (VNUT): appearance of an actress on the stage of purinergic signaling.The white gene of Drosophila melanogaster encodes a protein with a role in courtship behavior.Effect of Multi Drug Resistance Protein 4 (MRP4) Inhibition on the Pharmacokinetics and Pharmacodynamics of Ciprofloxacin in Normal and Rats with LPS-Induced Inflammation.Ca(2+) signaling occurs via second messenger release from intraorganelle synthesis sites.Essential role of vesicular nucleotide transporter in vesicular storage and release of nucleotides in platelets.Platelet granule exocytosis: a comparison with chromaffin cells.The sGC stimulator riociguat inhibits platelet function in washed platelets but not in whole blood.ABCC4 copy number variation is associated with susceptibility to esophageal squamous cell carcinoma.Changes of organic anion transporter MRP4 and related nuclear receptors in human obstructive cholestasis.
P2860
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P248
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P2860
The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The nucleotide transporter MRP ...... ing a role in mediator storage
@ast
The nucleotide transporter MRP ...... ing a role in mediator storage
@en
The nucleotide transporter MRP ...... ing a role in mediator storage
@en-gb
The nucleotide transporter MRP ...... ing a role in mediator storage
@nl
type
label
The nucleotide transporter MRP ...... ing a role in mediator storage
@ast
The nucleotide transporter MRP ...... ing a role in mediator storage
@en
The nucleotide transporter MRP ...... ing a role in mediator storage
@en-gb
The nucleotide transporter MRP ...... ing a role in mediator storage
@nl
prefLabel
The nucleotide transporter MRP ...... ing a role in mediator storage
@ast
The nucleotide transporter MRP ...... ing a role in mediator storage
@en
The nucleotide transporter MRP ...... ing a role in mediator storage
@en-gb
The nucleotide transporter MRP ...... ing a role in mediator storage
@nl
P2093
P921
P1433
P1476
The nucleotide transporter MRP ...... ing a role in mediator storage
@en
P2093
Gabriele Jedlitschky
Hendrik K Nieuwenhuis
Heyo K Kroemer
Jan W N Akkerman
Konstanze Tirschmann
Lena E Lubenow
P304
P356
10.1182/BLOOD-2003-12-4330
P407
P577
2004-12-01T00:00:00Z