DNAzymes to beta 1 and beta 3 mRNA down-regulate expression of the targeted integrins and inhibit endothelial cell capillary tube formation in fibrin and matrigel.
about
Binding of PAI-1 to endothelial cells stimulated by thymosin beta4 and modulation of their fibrinolytic potentialLocked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targetsChemosensitization of solid tumors by inhibition of Bcl-xL expression using DNAzyme.Matrix metalloproteinase-2 cleavage of the β1 integrin ectodomain facilitates colon cancer cell motility.Preclinical anticancer activity of DNA-based cleavage molecules.Brothers in arms: DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid-based gene-silencing strategies.Cancer, chitosan nanoparticles and catalytic nucleic acids.Theranostic DNAzymes.Therapeutic potential of siRNA and DNAzymes in cancer.RNA cleaving '10-23' DNAzymes with enhanced stability and activity.Structural rearrangements of the 10-23 DNAzyme to beta 3 integrin subunit mRNA induced by cations and their relations to the catalytic activity.DNA enzymes as potential therapeutics: towards clinical application of 10-23 DNAzymes.DNAzymes to mouse beta1 integrin mRNA in vivo: targeting the tumor vasculature and retarding cancer growth.Sequence-specific cleavage of RNA in the absence of divalent metal ions by a DNAzyme incorporating imidazolyl and amino functionalities.The synthesis and properties of oligoribonucleotide-spermine conjugates.DNA oligonucleotides containing stereodefined phosphorothioate linkages in selected positions.Inability of DNAzymes to cleave RNA in vivo is due to limited Mg[Formula: see text] concentration in cells.
P2860
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P2860
DNAzymes to beta 1 and beta 3 mRNA down-regulate expression of the targeted integrins and inhibit endothelial cell capillary tube formation in fibrin and matrigel.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
DNAzymes to beta 1 and beta 3 ...... mation in fibrin and matrigel.
@en
type
label
DNAzymes to beta 1 and beta 3 ...... mation in fibrin and matrigel.
@en
prefLabel
DNAzymes to beta 1 and beta 3 ...... mation in fibrin and matrigel.
@en
P2093
P2860
P356
P1476
DNAzymes to beta 1 and beta 3 ...... mation in fibrin and matrigel.
@en
P2093
Czeslaw S Cierniewski
Jolanta Niewiarowska
Magdalena Nawrot
Marcin Cieslak
Maria Koziolkiewicz
Wojciech J Stec
P2860
P304
P356
10.1074/JBC.M102325200
P407
P577
2001-10-23T00:00:00Z