Wild-type p53 and p73 negatively regulate expression of proliferation related genes.
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The transcription factor p53: not a repressor, solely an activatorAlterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53The p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genesA reduction of licensed origins reveals strain-specific replication dynamics in miceUdu deficiency activates DNA damage checkpoint.Genome and transcriptome profiling of fibrolamellar hepatocellular carcinoma demonstrates p53 and IGF2BP1 dysregulation.Unscheduled expression of CDC25B in S-phase leads to replicative stress and DNA damage.Loss of p73 promotes dissemination of Myc-induced B cell lymphomas in miceSynergistic chemosensitivity of triple-negative breast cancer cell lines to poly(ADP-Ribose) polymerase inhibition, gemcitabine, and cisplatinp53 Family and Cellular Stress Responses in Cancer.p53 and cell cycle dependent transcription of kinesin family member 23 (KIF23) is controlled via a CHR promoter element bound by DREAM and MMB complexes.PIM kinase inhibitor AZD1208 for treatment of MYC-driven prostate cancerEffects of TP53 mutational status on gene expression patterns across 10 human cancer types.Distinct mechanisms of inadequate erythropoiesis induced by tumor necrosis factor alpha or malarial pigment.Histone deacetylase inhibitor SAHA epigenetically regulates miR-17-92 cluster and MCM7 to upregulate MICA expression in hepatoma.Post-transcriptional homeostasis and regulation of MCM2-7 in mammalian cells.Gene and protein analysis reveals that p53 pathway is functionally inactivated in cytogenetically normal Acute Myeloid Leukemia and Acute Promyelocytic LeukemiaATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistanceCodon 104 variation of p53 gene provides adaptive apoptotic responses to extreme environments in mammals of the Tibet plateau.Transcriptional control of the proliferation cluster by the tumor suppressor p53.One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor.The TP73 complex network: ready for clinical translation in cancer?Census and evaluation of p53 target genes.Retinoblastoma-independent regulation of cell proliferation and senescence by the p53-p21 axis in lamin A /C-depleted cells.Crosstalk between c-Jun and TAp73alpha/beta contributes to the apoptosis-survival balance.Cdc25B is negatively regulated by p53 through Sp1 and NF-Y transcription factors.Identification of a p53-repressed gene module in breast cancer cells.Wild-type p53 binds to MYC promoter G-quadruplex.Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis.Dose- and time-dependent expression patterns of zebrafish orthologs of selected E2F target genes in response to serum starvation/replenishment.Cell cycle transcription control: DREAM/MuvB and RB-E2F complexes.Clinical implications of the deregulated TP73 isoforms expression in cancer.Lipoic acid induces p53-independent cell death in colorectal cancer cells and potentiates the cytotoxicity of 5-fluorouracil.Doxorubicin promotes transcriptional upregulation of Cdc25B in cancer cells by releasing Sp1 from the promoter.
P2860
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P2860
Wild-type p53 and p73 negatively regulate expression of proliferation related genes.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Wild-type p53 and p73 negatively regulate expression of proliferation related genes.
@en
type
label
Wild-type p53 and p73 negatively regulate expression of proliferation related genes.
@en
prefLabel
Wild-type p53 and p73 negatively regulate expression of proliferation related genes.
@en
P2093
P2860
P356
P1433
P1476
Wild-type p53 and p73 negatively regulate expression of proliferation related genes.
@en
P2093
E H Carchman
K E R Stagliano
L Mohanraj
M A E Anderson
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210898
P407
P577
2007-11-05T00:00:00Z
P5875
P6179
1005069153