Inhibition of DNA replication and induction of S phase cell cycle arrest by G-rich oligonucleotides.
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Accurate localization and relative quantification of arginine methylation using nanoflow liquid chromatography coupled to electron transfer dissociation and orbitrap mass spectrometryLuteolin modulates 6-hydroxydopamine-induced transcriptional changes of stress response pathways in PC12 cellsSuppression of tumor growth and angiogenesis by a specific antagonist of the cell-surface expressed nucleolinNucleolin is a calcium-binding proteinBioactivity of 2'-deoxyinosine-incorporated aptamer AS1411Vascular endothelial growth factor as an anti-angiogenic target for cancer therapyIdentification of different isoforms of eEF1A in the nuclear fraction of human T-lymphoblastic cancer cell line specifically binding to aptameric cytotoxic GT oligomers.Tolfenamic acid and pancreatic cancer growth, angiogenesis, and Sp protein degradation.Inactivation of nucleolin leads to nucleolar disruption, cell cycle arrest and defects in centrosome duplication.Structure-function analysis of nucleolin and ErbB receptors interactions.Surface expressed nucleolin is constantly induced in tumor cells to mediate calcium-dependent ligand internalization.Selection of Nucleic Acid Aptamers Targeting Tumor Cell-Surface Protein BiomarkersTargeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell typeNucleolin promotes in vitro translation of feline calicivirus genomic RNA.A new paradigm for aptamer therapeutic AS1411 action: uptake by macropinocytosis and its stimulation by a nucleolin-dependent mechanismBiophysical and biological properties of quadruplex oligodeoxyribonucleotidesDisrupting the oncogenic synergism between nucleolin and Ras results in cell growth inhibition and cell deathStructure-based drug design: from nucleic acid to membrane protein targets.Nucleolin down-regulation is involved in ADP-induced cell cycle arrest in S phase and cell apoptosis in vascular endothelial cells.PNAS-4, an Early DNA Damage Response Gene, Induces S Phase Arrest and Apoptosis by Activating Checkpoint Kinases in Lung Cancer Cells.Topical application of a G-Quartet aptamer targeting nucleolin attenuates choroidal neovascularization in a model of age-related macular degeneration.A phase II trial of AS1411 (a novel nucleolin-targeted DNA aptamer) in metastatic renal cell carcinomaTelomere homolog oligonucleotides and the skin: current status and future perspectives.Gene modulation for treating liver fibrosisTherapeutic applications of aptamers.Bioconjugation of oligonucleotides for treating liver fibrosis.Study of the Function of G-Rich Aptamers Selected for Lung AdenocarcinomaNucleolin-aptamer therapy in retinoblastoma: molecular changes and mass spectrometry-based imagingDiscovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancerDNA Walker-Regulated Cancer Cell Growth Inhibition.Aptamers as inhibitors of target proteins.2'-O-methyl-modified phosphorothioate antisense oligonucleotides have reduced non-specific effects in vitro.Transcription factor Sp1, also known as specificity protein 1 as a therapeutic target.Aptamer Internalization via Endocytosis Inducing S-Phase Arrest and Priming Maver-1 Lymphoma Cells for Cytarabine Chemotherapy.The G-quadruplex-forming aptamer AS1411 potently inhibits HIV-1 attachment to the host cell.Tumor targeting with a (99m)Tc-labeled AS1411 aptamer in prostate tumor cells.Interfering with the interaction between ErbB1, nucleolin and Ras as a potential treatment for glioblastoma.Interaction of G-rich GT oligonucleotides with nuclear-associated eEF1A is correlated with their antiproliferative effect in haematopoietic human cancer cell lines.Antiproliferative activity of a triplex-forming oligonucleotide recognizing a Ki-ras polypurine/polypyrimidine motif correlates with protein binding.Multifunctional G-quadruplex aptamers and their application to protein detection.
P2860
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P2860
Inhibition of DNA replication and induction of S phase cell cycle arrest by G-rich oligonucleotides.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Inhibition of DNA replication ...... st by G-rich oligonucleotides.
@en
type
label
Inhibition of DNA replication ...... st by G-rich oligonucleotides.
@en
prefLabel
Inhibition of DNA replication ...... st by G-rich oligonucleotides.
@en
P2093
P2860
P356
P1476
Inhibition of DNA replication ...... st by G-rich oligonucleotides.
@en
P2093
Hamhouyia F
McGregor WG
P2860
P304
43221-43230
P356
10.1074/JBC.M104446200
P407
P577
2001-09-12T00:00:00Z