Identification of a nucleolin binding site in human topoisomerase I
about
A novel nuclear localization signal in human DNA topoisomerase IPhosphorylation of DNA topoisomerase I by the c-Abl tyrosine kinase confers camptothecin sensitivityCell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activitiesSubnuclear distribution of topoisomerase I is linked to ongoing transcription and p53 statusInteraction between the N-terminus of human topoisomerase I and SV40 large T antigenInteraction between the N-terminal domain of human DNA topoisomerase I and the arginine-serine domain of its substrate determines phosphorylation of SF2/ASF splicing factorSUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damageRole for nucleolin/Nsr1 in the cellular localization of topoisomerase I.Mapping of a defined neurocan binding site to distinct domains of tenascin-CThe RNA-splicing factor PSF/p54 controls DNA-topoisomerase I activity by a direct interactionNucleolin: a multifunctional major nucleolar phosphoproteinImmunohistochemical analyses of DNA topoisomerase II isoforms in developing rat cerebellumResidues 190-210 of human topoisomerase I are required for enzyme activity in vivo but not in vitroCarrot cells contain two top1 genes having the coding capacity for two distinct DNA topoisomerases I.A DNA helicase from Pisum sativum is homologous to translation initiation factor and stimulates topoisomerase I activity.The role of histidine 632 in catalysis by human topoisomerase I.Autogenous translational regulation of the Borna disease virus negative control factor X from polycistronic mRNA using host RNA helicases.Myc induces the nucleolin and BN51 genes: possible implications in ribosome biogenesisDNA topoisomerase I in oncology: Dr Jekyll or Mr Hyde?Nucleolin Binds to the Proliferating Cell Nuclear Antigen and Inhibits Nucleotide Excision Repair.Targeting to transcriptionally active loci by the hydrophilic N-terminal domain of Drosophila DNA topoisomerase I.Human ARF protein interacts with topoisomerase I and stimulates its activity.A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol.Nuclear targeting by the growth factor midkine.Topoisomerase I requirement for death receptor-induced apoptotic nuclear fission.Mutational analysis of the preferential binding of human topoisomerase I to supercoiled DNA.DNA topoisomerase I domain interactions impact enzyme activity and sensitivity to camptothecin.Nucleolar function and size in cancer cellsCOPI coatomer complex proteins facilitate the translocation of anthrax lethal factor across vesicular membranes in vitro.Inhibition of DNA replication and induction of S phase cell cycle arrest by G-rich oligonucleotides.Nucleolin associates with the human cytomegalovirus DNA polymerase accessory subunit UL44 and is necessary for efficient viral replication.Poly(ADP-ribose) polymers regulate DNA topoisomerase I (Top1) nuclear dynamics and camptothecin sensitivity in living cells.Calcium-induced cleavage of DNA topoisomerase I involves the cytoplasmic-nuclear shuttling of calpain 2.Up-regulation of the KLF2 transcription factor by fluid shear stress requires nucleolin.Sumoylation of topoisomerase I is involved in its partitioning between nucleoli and nucleoplasm and its clearing from nucleoli in response to camptothecin.The N-terminal domain anchors human topoisomerase I at fibrillar centers of nucleoli and nucleolar organizer regions of mitotic chromosomes.Nucleolin, a novel partner for the Myb transcription factor family that regulates their activity.Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line. Cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3.Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.Nucleolin functions in the first step of ribosomal RNA processing.
P2860
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P2860
Identification of a nucleolin binding site in human topoisomerase I
description
1996 nî lūn-bûn
@nan
1996 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Identification of a nucleolin binding site in human topoisomerase I
@ast
Identification of a nucleolin binding site in human topoisomerase I
@en
Identification of a nucleolin binding site in human topoisomerase I
@nl
type
label
Identification of a nucleolin binding site in human topoisomerase I
@ast
Identification of a nucleolin binding site in human topoisomerase I
@en
Identification of a nucleolin binding site in human topoisomerase I
@nl
prefLabel
Identification of a nucleolin binding site in human topoisomerase I
@ast
Identification of a nucleolin binding site in human topoisomerase I
@en
Identification of a nucleolin binding site in human topoisomerase I
@nl
P2093
P2860
P921
P3181
P356
P1476
Identification of a nucleolin binding site in human topoisomerase I
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.271.4.1993
P407
P577
1996-01-26T00:00:00Z