Development of an interleukin (IL) 6 receptor antagonist that inhibits IL-6-dependent growth of human myeloma cells.
about
A viral gene that activates lytic cycle expression of Kaposi's sarcoma-associated herpesvirus.IL-6 type cytokine receptor complexes: hexamer, tetramer or both?Human herpesvirus 8 interleukin-6 (vIL-6) signals through gp130 but has structural and receptor-binding properties distinct from those of human IL-6.Correlation of peptide specificity and IgG subclass with pathogenic and nonpathogenic autoantibodies in pemphigus vulgaris: a model for autoimmunityThe therapeutic potential of interleukin-6 hyperagonists and antagonists.Interleukin-6: structure-function relationships.The interleukin-6 (IL-6) partial antagonist (Q159E,T162P)IL-6 interacts with the IL-6 receptor and gp130 but fails to induce a stable hexameric receptor complex.Analysis of the mechanism of action of anti-human interleukin-6 and anti-human interleukin-6 receptor-neutralising monoclonal antibodies.An antagonist for the leukemia inhibitory factor receptor inhibits leukemia inhibitory factor, cardiotrophin-1, ciliary neurotrophic factor, and oncostatin M.Interleukin-6 (IL-6) antagonism by soluble IL-6 receptor alpha mutated in the predicted gp130-binding interface.Multiple myeloma: increasing evidence for a multistep transformation process.Functional implications of large backbone amplitude motions of the glycoprotein 130-binding epitope of interleukin-6.Interleukin-6 N-terminal peptides modulate the expression of junB protooncogene and the production of fibrinogen in HepG2 cells.From Poisson distribution to interleukins.Recombinant human single chain Fv antibodies recognizing human interleukin-6. Specific targeting of cytokine-secreting cells.Identification of residues in the putative 5th helical region of human interleukin-6, important for activation of the IL-6 signal transducer, gp130.Definition of a Composite Binding Site for gp130 in Human Interleukin-6
P2860
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P2860
Development of an interleukin (IL) 6 receptor antagonist that inhibits IL-6-dependent growth of human myeloma cells.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Development of an interleukin ...... growth of human myeloma cells.
@en
type
label
Development of an interleukin ...... growth of human myeloma cells.
@en
prefLabel
Development of an interleukin ...... growth of human myeloma cells.
@en
P2093
P2860
P356
P1476
Development of an interleukin ...... growth of human myeloma cells
@en
P2093
F D de Hon
J P Brakenhoff
L A Aarden
S B Ebeling
P2860
P304
P356
10.1084/JEM.180.6.2395
P407
P577
1994-12-01T00:00:00Z