Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766.
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Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transductionUbiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosisNedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and functionFRS2 alpha attenuates FGF receptor signaling by Grb2-mediated recruitment of the ubiquitin ligase Cbl.Genetic insights into the mechanisms of Fgf signalingEndocytosis and Trafficking of Natriuretic Peptide Receptor-A: Potential Role of Short Sequence MotifsDefective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasiaFGF acts as a co-transmitter through adenosine A(2A) receptor to regulate synaptic plasticityRegulation of endocytosis, nuclear translocation, and signaling of fibroblast growth factor receptor 1 by E-cadherin.Down-regulation of cell surface receptors is modulated by polar residues within the transmembrane domain.Spatio-temporally precise activation of engineered receptor tyrosine kinases by light.Ligand-mediated endocytosis and intracellular sequestration of guanylyl cyclase/natriuretic peptide receptors: role of GDAY motifFGF21 promotes endothelial cell angiogenesis through a dynamin-2 and Rab5 dependent pathway.Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryosFGFR1 cleavage and nuclear translocation regulates breast cancer cell behavior.Fgfr1 regulates development through the combinatorial use of signaling proteins.Activation of Cardiac Fibroblast Growth Factor Receptor 4 Causes Left Ventricular HypertrophyA truncated K-sam product lacking the distal carboxyl-terminal portion provides a reduced level of autophosphorylation and greater resistance against induction of differentiationEpidermal growth factor signaling and mitogenesis in Plcg1 null mouse embryonic fibroblasts.Grb2, a double-edged sword of receptor tyrosine kinase signalingDistinct cellular properties of oncogenic KIT receptor tyrosine kinase mutants enable alternative courses of cancer cell inhibitionLigand-induced EpoR internalization is mediated by JAK2 and p85 and is impaired by mutations responsible for primary familial and congenital polycythemiaDegradation of activated protein kinases by ubiquitination.Uptake and intracellular transport of acidic fibroblast growth factor: evidence for free and cytoskeleton-anchored fibroblast growth factor receptors.In situ imaging of quantum dot-AZD4547 conjugates for tracking the dynamic behavior of fibroblast growth factor receptor 3.Fibroblast growth factor receptor 2 phosphorylation on serine 779 couples to 14-3-3 and regulates cell survival and proliferation.The transmembrane mutation G380R in fibroblast growth factor receptor 3 uncouples ligand-mediated receptor activation from down-regulation.Fasting-induced hormonal regulation of lysosomal function.Antibody-induced dimerization of FGFR1 promotes receptor endocytosis independently of its kinase activity.Ligation of the alpha 2-macroglobulin signalling receptor on macrophages induces protein phosphorylation and an increase in cytosolic pH.Endocytosis of Fgf8 is a double-stage process and regulates spreading and signaling.A threshold model for receptor tyrosine kinase signaling specificity and cell fate determination.
P2860
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P2860
Internalization of fibroblast growth factor receptor is inhibited by a point mutation at tyrosine 766.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Internalization of fibroblast ...... oint mutation at tyrosine 766.
@en
type
label
Internalization of fibroblast ...... oint mutation at tyrosine 766.
@en
prefLabel
Internalization of fibroblast ...... oint mutation at tyrosine 766.
@en
P1476
Internalization of fibroblast ...... point mutation at tyrosine 766
@en
P2093
Schlessinger J
P304
17056-17061
P407
P577
1994-06-01T00:00:00Z