Transglutaminase-dependent RhoA activation and depletion by serotonin in vascular smooth muscle cells.
about
Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylationSerotonylation of vascular proteins important to contractionHistaminylation of glutamine residues is a novel posttranslational modification implicated in G-protein signalingRho GTPase regulation by miRNAs and covalent modificationsTransglutaminase 2-mediated serotonylation in pulmonary hypertensionThe redox state of transglutaminase 2 controls arterial remodelingImmunomodulatory effects mediated by serotoninCellular functions of tissue transglutaminasePhospholipase C, Ca2+, and calmodulin signaling are required for 5-HT2A receptor-mediated transamidation of Rac1 by transglutaminaseSerotonergic dystrophy induced by excess serotonin.Valvular dystrophy associated filamin A mutations reveal a new role of its first repeats in small-GTPase regulation.Transglutaminase 2 overexpression induces depressive-like behavior and impaired TrkB signaling in miceCell signaling by protein carbonylation and decarbonylation.Neuroendocrine signaling via the serotonin transporter regulates clearance of apoptotic cells.New approaches to the treatment of pulmonary hypertension: from bench to bedside.Transglutaminase regulation of cell function.Altered gene expression in pulmonary tissue of tryptophan hydroxylase-1 knockout mice: implications for pulmonary arterial hypertension.Serotonin potentiates transforming growth factor-beta3 induced biomechanical remodeling in avian embryonic atrioventricular valves.RhoA/Rho-kinase and vascular diseases: what is the link?An in vivo tagging method reveals that Ras undergoes sustained activation upon transglutaminase-mediated protein serotonylation.Modification of proteins by norepinephrine is important for vascular contraction.Communication between 5-HT and small GTPases.The expanded biology of serotonin.Effect of chronic perinatal hypoxia on the role of rho-kinase in pulmonary artery contraction in newborn lambs.Brief serotonin exposure initiates arteriolar inward remodeling processes in vivo that involve transglutaminase activation and actin cytoskeleton reorganization.Simvastatin improves the homing of BMSCs via the PI3K/AKT/miR-9 pathway.Rho GTPase-activating bacterial toxins: from bacterial virulence regulation to eukaryotic cell biology.Serotonin-mediated protein carbonylation in the right heart.Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertensionNovel interactions between the 5-HT transporter, 5-HT1B receptors and Rho kinase in vivo and in pulmonary fibroblastsTransglutaminase 2 is central to induction of the arterial calcification program by smooth muscle cellsTransglutaminase 2 regulates the GTPase-activating activity of Bcr.RhoA/Rho-kinase signaling: a therapeutic target in pulmonary hypertension.Novel roles for biogenic monoamines: from monoamines in transglutaminase-mediated post-translational protein modification to monoaminylation deregulation diseases.Targeting RhoA/ROCK pathway in pulmonary arterial hypertension.Smooth muscle cell hypertrophy, proliferation, migration and apoptosis in pulmonary hypertension.Role of the serotonin transporter in pulmonary arterial hypertension.Interactions between integrin alphaIIbbeta3 and the serotonin transporter regulate serotonin transport and platelet aggregation in mice and humans.Tissue transglutaminase promotes serotonin-induced AKT signaling and mitogenesis in pulmonary vascular smooth muscle cells.Role of protein transamidation in serotonin-induced proliferation and migration of pulmonary artery smooth muscle cells
P2860
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P2860
Transglutaminase-dependent RhoA activation and depletion by serotonin in vascular smooth muscle cells.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Transglutaminase-dependent Rho ...... vascular smooth muscle cells.
@en
type
label
Transglutaminase-dependent Rho ...... vascular smooth muscle cells.
@en
prefLabel
Transglutaminase-dependent Rho ...... vascular smooth muscle cells.
@en
P2093
P50
P356
P1476
Transglutaminase-dependent Rho ...... n vascular smooth muscle cells
@en
P2093
Gerry Melino
Malvyne Rolli-Derkinderen
Pierre Pacaud
P304
P356
10.1074/JBC.M604195200
P407
P577
2006-12-02T00:00:00Z