about
Under Pressure: Mechanical Stress Management in the NucleusFocal adhesions, stress fibers and mechanical tensionFrom mechanical force to RhoA activationNuclear mechanotransduction: forcing the nucleus to respondInhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertensionSte20-related kinase SLK phosphorylates Ser188 of RhoA to induce vasodilation in response to angiotensin II Type 2 receptor activationRegulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathwayVinculin phosphorylation differentially regulates mechanotransduction at cell-cell and cell-matrix adhesionsHaemodynamic and extracellular matrix cues regulate the mechanical phenotype and stiffness of aortic endothelial cells.Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cellsThe small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signalsIsolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus.Increased Rho-kinase expression and activity and pulmonary endothelial dysfunction in smokers with normal lung function.Using magnets and magnetic beads to dissect signaling pathways activated by mechanical tension applied to cellsRho protein crosstalk: another social network?Transglutaminase-dependent RhoA activation and depletion by serotonin in vascular smooth muscle cells.Mechanically induced focal adhesion assembly amplifies anti-adipogenic pathways in mesenchymal stem cells.The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration.Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads.Mechanotransduction via the nuclear envelope: a distant reflection of the cell surface.The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure.Colorectal Cancer Cells Adhere to and Migrate Along the Neurons of the Enteric Nervous System.RhoA and Rho kinase activation in human pulmonary hypertension: role of 5-HT signaling.AMPK alpha 1-induced RhoA phosphorylation mediates vasoprotective effect of estradiol.Analysis of RhoA and Rho GEF activity in whole cells and the cell nucleus.Hyaluronan induces vascular smooth muscle cell migration through RHAMM-mediated PI3K-dependent Rac activation.Analyzing Mechanotransduction Through the LINC Complex in Isolated NucleiScavenger Receptor Cysteine-Rich domains of Lysyl Oxidase-Like2 regulate endothelial ECM and angiogenesis through non-catalytic scaffolding mechanismsRRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndromeNuclear envelope deformation controls cell cycle progression in response to mechanical forceSyndecan-4 forces integrins to cooperate
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Christophe Guilluy
@ast
Christophe Guilluy
@en
Christophe Guilluy
@es
Christophe Guilluy
@nl
Christophe Guilluy
@sl
type
label
Christophe Guilluy
@ast
Christophe Guilluy
@en
Christophe Guilluy
@es
Christophe Guilluy
@nl
Christophe Guilluy
@sl
prefLabel
Christophe Guilluy
@ast
Christophe Guilluy
@en
Christophe Guilluy
@es
Christophe Guilluy
@nl
Christophe Guilluy
@sl
P1053
C-6002-2014
P106
P108
P21
P31
P3829
P496
0000-0003-1141-0809