HMG-domain protein recognition of cisplatin 1,2-intrastrand d(GpG) cross-links in purine-rich sequence contexts.
about
DNA and the chromosome - varied targets for chemotherapySolution Structures of a DNA Dodecamer Duplex with and without a Cisplatin 1,2-d(GG) Intrastrand Cross-Link: Comparison with the Same DNA Duplex Containing an Oxaliplatin 1,2-d(GG) Intrastrand Cross-Link † , ‡Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-LinksA new, but old, nucleoside analog: the first synthesis of 1-deaza-2'-deoxyguanosine and its properties as a nucleoside and as oligodeoxynucleotidesMinor groove deformability of DNA: a molecular dynamics free energy simulation study.Sequence-specific recognition of cancer drug-DNA adducts by HMGB1a repair proteinStructural basis for the sequence-dependent effects of platinum-DNA adducts.Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable siteDNA bending and unwinding due to the major 1,2-GG intrastrand cross-link formed by antitumor cis-diamminedichloroplatinum(II) are flanking-base independent.Effects of spectator ligands on the specific recognition of intrastrand platinum-DNA cross-links by high mobility group box and TATA-binding proteins.DNA-protein cross-linking by trans-[PtCl(2)(E-iminoether)(2)]. A concept for activation of the trans geometry in platinum antitumor complexesSpecific interaction of p53 with target binding sites is determined by DNA conformation and is regulated by the C-terminal domain.Mechanistic studies of the modulation of cleavage activity of topoisomerase I by DNA adducts of mono- and bi-functional PtII complexes.Molecular dynamic simulations of cisplatin- and oxaliplatin-d(GG) intrastand cross-links reveal differences in their conformational dynamicsCisplatin adducts on a GGG sequence within a DNA duplex studied by NMR spectroscopy and molecular dynamics simulations.DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464. Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair.Translesion DNA synthesis across double-base lesions derived from cross-links of an antitumor trinuclear platinum compound: primer extension, conformational and thermodynamic studies.Binding of piano-stool Ru(II) complexes to DNA; QM/MM study.Reactions of cisplatin and glycine in solution with constant pH: a computational study.
P2860
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P2860
HMG-domain protein recognition of cisplatin 1,2-intrastrand d(GpG) cross-links in purine-rich sequence contexts.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
HMG-domain protein recognition ...... purine-rich sequence contexts.
@en
type
label
HMG-domain protein recognition ...... purine-rich sequence contexts.
@en
prefLabel
HMG-domain protein recognition ...... purine-rich sequence contexts.
@en
P2093
P356
P1433
P1476
HMG-domain protein recognition ...... purine-rich sequence contexts.
@en
P2093
P304
11771-11776
P356
10.1021/BI001352L
P407
P50
P577
2000-09-01T00:00:00Z