Cisplatin adducts on a GGG sequence within a DNA duplex studied by NMR spectroscopy and molecular dynamics simulations.

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Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-Links Mechanism of interstrand migration of organoruthenium anticancer complexes within a DNA duplex.On the complexity and dynamics of in vivo Cisplatin-DNA adduct formation using HPLC/ICP-MS.

P2860

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P2860

Cisplatin adducts on a GGG sequence within a DNA duplex studied by NMR spectroscopy and molecular dynamics simulations.

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http://www.wikidata.org/entity/Q43265231

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2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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Cisplatin adducts on a GGG seq ...... olecular dynamics simulations.

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Cisplatin adducts on a GGG seq ...... olecular dynamics simulations.

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Item

label

Cisplatin adducts on a GGG seq ...... olecular dynamics simulations.

@en

Cisplatin adducts on a GGG seq ...... olecular dynamics simulations.

@nl

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Cisplatin adducts on a GGG seq ...... olecular dynamics simulations.

@en

Cisplatin adducts on a GGG seq ...... olecular dynamics simulations.

@nl

P1476

Cisplatin adducts on a GGG seq ...... olecular dynamics simulations.

@en

P2093

Einar Sletten

http://www.w3.org/2001/XMLSchema#string

Jirí Kozelka

http://www.w3.org/2001/XMLSchema#string

Stéphane Téletchéa

http://www.w3.org/2001/XMLSchema#string

Tormod Skauge

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P2860

Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins

Relationship of solution and protein-bound structures of DNA duplexes with the major intrastrand cross-link lesions formed on cisplatin binding to DNA

2.4 A crystal structure of an oxaliplatin 1,2-d(GpG) intrastrand cross-link in a DNA dodecamer duplex

Solution Structures of a DNA Dodecamer Duplex with and without a Cisplatin 1,2-d(GG) Intrastrand Cross-Link: Comparison with the Same DNA Duplex Containing an Oxaliplatin 1,2-d(GG) Intrastrand Cross-Link † , ‡

Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin

Unrestrained 5 ns molecular dynamics simulation of a cisplatin-DNA 1,2-GG adduct provides a rationale for the NMR features and reveals increased conformational flexibility at the platinum binding site.

Determination of sugar conformations by NMR in larger DNA duplexes using both dipolar and scalar data: application to d(CATGTGACGTCACATG)2.

Solution structure of the CpG containing d(CTTCGAAG)2 oligonucleotide: NMR data and energy calculations are compatible with a BI/BII equilibrium at CpG.

HMG-domain protein recognition of cisplatin 1,2-intrastrand d(GpG) cross-links in purine-rich sequence contexts.

A pyrazolato-bridged dinuclear platinum(II) complex induces only minor distortions upon DNA-binding.

P304

12320-12337

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P31

scholarly article

P356

10.1002/CHEM.200901158

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P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2009-11-01T00:00:00Z

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P5875

26879980

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P698

19813235

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Cisplatin adducts on a GGG sequence within a DNA duplex studied by NMR spectroscopy and molecular dynamics simulations.

about

P2860

P2860

Cisplatin adducts on a GGG sequence within a DNA duplex studied by NMR spectroscopy and molecular dynamics simulations.

description

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type

label

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698