Smad7 mediates apoptosis induced by transforming growth factor beta in prostatic carcinoma cells.
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Smad7 stabilizes beta-catenin binding to E-cadherin complex and promotes cell-cell adhesionSmad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55Jab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradationTransforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosisInhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARAGonadotropin releasing hormone analogue (GnRHa) alters the expression and activation of Smad in human endometrial epithelial and stromal cellsSmad7 is induced by CD40 and protects WEHI 231 B-lymphocytes from transforming growth factor-beta -induced growth inhibition and apoptosisChromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signalingAntagonistic effects of Smad2 versus Smad7 are sensitive to their expression level during tooth developmentDecreased Smad 7 expression contributes to cardiac fibrosis in the infarcted rat heartSIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylationAssociation between endogenous gene expression and growth regulation induced by TGF-beta1 in human gastric cancer cellsCritical role of Smads and AP-1 complex in transforming growth factor-beta -dependent apoptosis.Conditional epidermal expression of TGFbeta 1 blocks neonatal lethality but causes a reversible hyperplasia and alopeciaTGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responsesTransforming growth factor beta-dependent sequential activation of Smad, Bim, and caspase-9 mediates physiological apoptosis in gastric epithelial cells.Deficiency of biglycan causes cardiac fibroblasts to differentiate into a myofibroblast phenotype.Transforming growth factor-beta 1 induces apoptosis through Fas ligand-independent activation of the Fas death pathway in human gastric SNU-620 carcinoma cells.Evidence for an Important Role of Smad-7 in Intervertebral Disc Degeneration.Apoptosis in podocytes induced by TGF-beta and Smad7Gene expression profiling identifies lobe-specific and common disruptions of multiple gene networks in testosterone-supported, 17beta-estradiol- or diethylstilbestrol-induced prostate dysplasia in Noble rats.Synergistic induction of follicle-stimulating hormone beta-subunit gene expression by gonadal steroid hormone receptors and Smad proteinsThe Smad7-Skp2 complex orchestrates Myc stability, impacting on the cytostatic effect of TGF-βProstate cancer: the need for biomarkers and new therapeutic targets.Smad7: not only a regulator, but also a cross-talk mediator of TGF-β signalling.The dual role of Smad7 in the control of cancer growth and metastasis.Smad7 is required for TGF-beta-induced activation of the small GTPase Cdc42.Are SMAD7 rs4939827 and CHI3L1 rs4950928 polymorphisms associated with colorectal cancer in Egyptian patients?Regulation of TGF-β Family Signaling by Inhibitory Smads.APC and Smad7 link TGFβ type I receptors to the microtubule system to promote cell migration.Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues.Tid1 is a Smad-binding protein that can modulate Smad7 activity in developing embryos.AIP4 restricts transforming growth factor-beta signaling through a ubiquitination-independent mechanism.2-Methoxyestradiol-induced apoptosis in prostate cancer cells requires Smad7.Evidence for a role of the JNK cascade in Smad7-mediated apoptosis.Meeting report: signaling schemes for TGF-beta.Necessary role of phosphatidylinositol 3-kinase in transforming growth factor beta-mediated activation of Akt in normal and rheumatoid arthritis synovial fibroblasts.Smad and p38-MAPK signaling mediates apoptotic effects of transforming growth factor-beta1 in human airway epithelial cells.
P2860
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P2860
Smad7 mediates apoptosis induced by transforming growth factor beta in prostatic carcinoma cells.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Smad7 mediates apoptosis induc ...... in prostatic carcinoma cells.
@en
type
label
Smad7 mediates apoptosis induc ...... in prostatic carcinoma cells.
@en
prefLabel
Smad7 mediates apoptosis induc ...... in prostatic carcinoma cells.
@en
P2093
P1433
P1476
Smad7 mediates apoptosis induc ...... in prostatic carcinoma cells.
@en
P2093
Hermansson A
Landström M
ten Dijke P
P304
P356
10.1016/S0960-9822(00)00470-X
P407
P577
2000-05-01T00:00:00Z