siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts.
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A TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcriptionAML1/ETO proteins control POU4F1/BRN3A expression and function in t(8;21) acute myeloid leukemiaA distinct epigenetic signature at targets of a leukemia protein.Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia.RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML.Effects of the NUP98-DDX10 oncogene on primary human CD34+ cells: role of a conserved helicase motifAML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2V617F-independent overexpression of NF-E2Identification of a dynamic core transcriptional network in t(8;21) AML that regulates differentiation block and self-renewal.PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potentialThe thrombopoietin/MPL/Bcl-xL pathway is essential for survival and self-renewal in human preleukemia induced by AML1-ETO.Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding.RUNX1T1: a novel predictor of liver metastasis in primary pancreatic endocrine neoplasmsGenome-wide discovery of functional transcription factor binding sites by comparative genomics: the case of Stat3.A Drosophila model identifies calpains as modulators of the human leukemogenic fusion protein AML1-ETOEpigenetic mechanisms regulating normal and malignant haematopoiesis: new therapeutic targets for clinical medicine.Chromosomal aberrations and fusion genes in myeloid malignancies.The multi-functional cellular adhesion molecule CD44 is regulated by the 8;21 chromosomal translocation.Esculetin Downregulates the Expression of AML1-ETO and C-Kit in Kasumi-1 Cell Line by Decreasing Half-Life of mRNA.AML1-ETO targets and suppresses cathepsin G, a serine protease, which is able to degrade AML1-ETO in t(8;21) acute myeloid leukemia.Interference with RUNX1/ETO leukemogenic function by cell-penetrating peptides targeting the NHR2 oligomerization domain.Developmental-stage-dependent transcriptional response to leukaemic oncogene expression.High sensitivity and label-free oligonucleotides detection using photonic bandgap sensing structures biofunctionalized with molecular beacon probes.CD31, EDNRB and TSPAN7 are promising prognostic markers in clear-cell renal cell carcinoma revealed by genome-wide expression analyses of primary tumors and metastases.Integrated epigenetic and genetic analysis identifies markers of prognostic significance in pediatric acute myeloid leukemia.Glucocorticoids Inhibit Oncogenic RUNX1-ETO in Acute Myeloid Leukemia with Chromosome Translocation t(8;21).The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation
P2860
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P2860
siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
siRNA-mediated AML1/MTG8 deple ...... lines and primary AML blasts.
@en
type
label
siRNA-mediated AML1/MTG8 deple ...... lines and primary AML blasts.
@en
prefLabel
siRNA-mediated AML1/MTG8 deple ...... lines and primary AML blasts.
@en
P2093
P2860
P356
P1433
P1476
siRNA-mediated AML1/MTG8 deple ...... l lines and primary AML blasts
@en
P2093
A Neubauer
B Drescher
C Cullmann
N Martinez Soria
O Hartmann
P2860
P2888
P304
P356
10.1038/SJ.ONC.1209638
P407
P577
2006-05-01T00:00:00Z
P5875
P6179
1044517069