Genome-wide discovery of functional transcription factor binding sites by comparative genomics: the case of Stat3.
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On the immortality of television sets: "function" in the human genome according to the evolution-free gospel of ENCODESH2B1β interacts with STAT3 and enhances fibroblast growth factor 1-induced gene expression during neuronal differentiationThe impact of anti-inflammatory cytokines on the pancreatic β-cellHuman mutations affect the epigenetic/bookmarking function of HNF1BDistance and helical phase dependence of synergistic transcription activation in cis-regulatory moduleApplication of experimentally verified transcription factor binding sites models for computational analysis of ChIP-Seq data.Prediction and experimental validation of novel STAT3 target genes in human cancer cellsSTAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia.Identification of functional TFAP2A and SP1 binding sites in new TFAP2A-modulated genesStat3 regulates desmoglein 3 transcription in epithelial keratinocytes.Plasma metalloproteinase levels are dysregulated in signal transducer and activator of transcription 3 mutated hyper-IgE syndromeEgr1 protein acts downstream of estrogen-leukemia inhibitory factor (LIF)-STAT3 pathway and plays a role during implantation through targeting Wnt4.STAT3 controls myeloid progenitor growth during emergency granulopoiesis.Optimizing the GATA-3 position weight matrix to improve the identification of novel binding sites.Cross-talk among myeloid-derived suppressor cells, macrophages, and tumor cells impacts the inflammatory milieu of solid tumors.Comprehensive genome-wide transcription factor analysis reveals that a combination of high affinity and low affinity DNA binding is needed for human gene regulation.Stat3-mediated activation of microRNA-23a suppresses gluconeogenesis in hepatocellular carcinoma by down-regulating glucose-6-phosphatase and peroxisome proliferator-activated receptor gamma, coactivator 1 alphaDistinct transcriptional regulatory modules underlie STAT3's cell type-independent and cell type-specific functions.NEAT1 modulates herpes simplex virus-1 replication by regulating viral gene transcription.The IL-10/STAT3-mediated anti-inflammatory response: recent developments and future challenges.Genomic and computational approaches to dissect the mechanisms of STAT3's universal and cell type-specific functions.STAT3 and metabolism: how many ways to use a single molecule?Phosphorylated STAT3 physically interacts with NPM and transcriptionally enhances its expression in cancer.Identification of functional cis-regulatory polymorphisms in the human genome.Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.The RhoU/Wrch1 Rho GTPase gene is a common transcriptional target of both the gp130/STAT3 and Wnt-1 pathways.Endothelial STAT3 Modulates Protective Mechanisms in a Mouse Ischemia-Reperfusion Model of Acute Kidney Injury.Hepatocyte Nuclear Factor-1β Controls Mitochondrial Respiration in Renal Tubular Cells.Psoriasis: A STAT3-Centric View.MITF - A controls branching morphogenesis and nephron endowment.IRF4 Mediates the Oncogenic Effects of STAT3 in Anaplastic Large Cell Lymphomas.Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis.Stat3 Controls Tubulointerstitial Communication during CKD.The immediate early genes Fos and Egr1 become STAT1 transcriptional targets in the absence of STAT3Cyclin D1 is a direct transcriptional target of GATA3 in neuroblastoma tumor cellsNucleus, Mitochondrion, or Reticulum? STAT3 à La CarteSTAT3 in Skeletal Muscle Function and Disorders
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P2860
Genome-wide discovery of functional transcription factor binding sites by comparative genomics: the case of Stat3.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 12 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Genome-wide discovery of funct ...... e genomics: the case of Stat3.
@en
Genome-wide discovery of funct ...... e genomics: the case of Stat3.
@nl
type
label
Genome-wide discovery of funct ...... e genomics: the case of Stat3.
@en
Genome-wide discovery of funct ...... e genomics: the case of Stat3.
@nl
prefLabel
Genome-wide discovery of funct ...... e genomics: the case of Stat3.
@en
Genome-wide discovery of funct ...... e genomics: the case of Stat3.
@nl
P2093
P2860
P50
P356
P1476
Genome-wide discovery of funct ...... e genomics: the case of Stat3.
@en
P2093
Davide Schiavone
Francesco Vallania
Marco Pontoglio
Paolo Provero
Sarah Dewilde
Serge Garbay
P2860
P304
P356
10.1073/PNAS.0900473106
P407
P577
2009-03-12T00:00:00Z