Translation-dependent displacement of UPF1 from coding sequences causes its enrichment in 3' UTRs.
about
Nonsense-mediated mRNA decay: novel mechanistic insights and biological impactMechanism and regulation of the nonsense-mediated decay pathwayRNA Binding Proteins in the miRNA PathwayRetroviral strategy to stabilize viral RNAThe Clothes Make the mRNA: Past and Present Trends in mRNP FashionNonsense-mediated mRNA decay in humans at a glanceNonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the StoryOrganizing principles of mammalian nonsense-mediated mRNA decayEukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay by two genetically separable mechanismsHIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA.Human Upf1 is a highly processive RNA helicase and translocase with RNP remodelling activitiesRNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis.A post-translational regulatory switch on UPF1 controls targeted mRNA degradationHuman nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes.MicroRNA-mediated repression of nonsense mRNAs.Non-coding RNA: a new frontier in regulatory biology.Glucocorticoid receptor interacts with PNRC2 in a ligand-dependent manner to recruit UPF1 for rapid mRNA degradation.The unfolded protein response is shaped by the NMD pathwayImmunity of the Saccharomyces cerevisiae SSY5 mRNA to nonsense-mediated mRNA decay.NMD: At the crossroads between translation termination and ribosome recycling.Nonsense-mediated RNA decay--a switch and dial for regulating gene expressionA critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors.Identification of Interactions in the NMD Complex Using Proximity-Dependent Biotinylation (BioID).Chromatoid Body Protein TDRD6 Supports Long 3' UTR Triggered Nonsense Mediated mRNA Decay.UPF2-Dependent Nonsense-Mediated mRNA Decay Pathway Is Essential for Spermatogenesis by Selectively Eliminating Longer 3'UTR Transcripts.A multiprotein occupancy map of the mRNP on the 3' end of histone mRNAs.The role of nucleotide composition in premature termination codon recognition.A system for coordinated analysis of translational readthrough and nonsense-mediated mRNA decay.Target Discrimination in Nonsense-Mediated mRNA Decay Requires Upf1 ATPase ActivityRecent transcriptome-wide mapping of UPF1 binding sites reveals evidence for its recruitment to mRNA before translation.Polypyrimidine tract binding protein 1 protects mRNAs from recognition by the nonsense-mediated mRNA decay pathway.Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complexThe PUF binding landscape in metazoan germ cells.Viral Evasion and Manipulation of Host RNA Quality Control Pathways.ATP hydrolysis by UPF1 is required for efficient translation termination at premature stop codons.Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6- and SMG7-mediated degradation pathways.Therapeutics based on stop codon readthrough.In vivo determination of direct targets of the nonsense-mediated decay pathway in Drosophila.MicroRNA binding sites in the coding region of mRNAs: extending the repertoire of post-transcriptional gene regulation.Mechanism, factors, and physiological role of nonsense-mediated mRNA decay.
P2860
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P2860
Translation-dependent displacement of UPF1 from coding sequences causes its enrichment in 3' UTRs.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Translation-dependent displace ...... ses its enrichment in 3' UTRs.
@en
type
label
Translation-dependent displace ...... ses its enrichment in 3' UTRs.
@en
prefLabel
Translation-dependent displace ...... ses its enrichment in 3' UTRs.
@en
P2860
P50
P356
P1476
Translation-dependent displace ...... ses its enrichment in 3' UTRs.
@en
P2093
David Zünd
P2860
P2888
P304
P356
10.1038/NSMB.2635
P577
2013-07-07T00:00:00Z
P5875
P6179
1034840041