The C-terminal conserved domain of DNA-PKcs, missing in the SCID mouse, is required for kinase activity.
about
Mutational analysis of the C-terminal FATC domain of Saccharomyces cerevisiae Tra1.The C-terminal residues of Saccharomyces cerevisiae Mec1 are required for its localization, stability, and function.Late activation of stress kinases (SAPK/JNK) by genotoxins requires the DNA repair proteins DNA-PKcs and CSBToll-like receptor 9-induced type I IFN protects mice from experimental colitis.DNA-PKcs is critical for telomere cappingA single amino acid substitution in DNA-PKcs explains the novel phenotype of the CHO mutant, XR-C2.DNA repair kinetics in SCID mice Sertoli cells and DNA-PKcs-deficient mouse embryonic fibroblasts.Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining.The catalytic subunit of DNA-protein kinase (DNA-PKcs) is not required for Ig class-switch recombinationThe role of the non-homologous end-joining pathway in lymphocyte development.The life and death of DNA-PK.Genetic evidence links the ASTRA protein chaperone component Tti2 to the SAGA transcription factor Tra1.DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity.Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks.DNA-dependent protein kinase activity is not required for immunoglobulin class switching.The N-terminal region of the DNA-dependent protein kinase catalytic subunit is required for its DNA double-stranded break-mediated activation.p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK.DNA double strand break repair via non-homologous end-joining.Non-homologous end joining in class switch recombination: the beginning of the endTip60: connecting chromatin to DNA damage signaling.Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2.DNA-dependent protein kinase-mediated phosphorylation of protein kinase B requires a specific recognition sequence in the C-terminal hydrophobic motif.Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity.Role of DNA-dependent protein kinase in neuronal survival.Hair Follicle Stem Cell Faith Is Dependent on Chromatin Remodeling Capacity Following Low-Dose Radiation.Elevated DNA double strand breaks and apoptosis in the CNS of scid mutant mice.Molecular Evidence of Genome Editing in a Mouse Model of Immunodeficiency.
P2860
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P2860
The C-terminal conserved domain of DNA-PKcs, missing in the SCID mouse, is required for kinase activity.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
The C-terminal conserved domai ...... required for kinase activity.
@en
type
label
The C-terminal conserved domai ...... required for kinase activity.
@en
prefLabel
The C-terminal conserved domai ...... required for kinase activity.
@en
P2093
P2860
P356
P1476
The C-terminal conserved domai ...... required for kinase activity.
@en
P2093
Beamish HJ
Jessberger R
Priestley A
P2860
P304
P356
10.1093/NAR/28.7.1506
P407
P577
2000-04-01T00:00:00Z