DNA polymerase epsilon: aphidicolin inhibition and the relationship between polymerase and exonuclease activity.
about
Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleasesICBP90 belongs to a new family of proteins with an expression that is deregulated in cancer cellsEnzymatic processing of replication and recombination intermediates by the vaccinia virus DNA polymeraseDNA polymerase θ (POLQ), double-strand break repair, and cancerThe retinoblastoma gene and its product are targeted by ICBP90: a key mechanism in the G1/S transition during the cell cycleDNA secondary structure at chromosomal fragile sites in human disease.Human mismatch repair: reconstitution of a nick-directed bidirectional reaction.Impaired replication stress response in cells from immunodeficiency patients carrying Cernunnos/XLF mutations.Secondary structure formation and DNA instability at fragile site FRA16BDNA instability at chromosomal fragile sites in cancerHuman CST promotes telomere duplex replication and general replication restart after fork stalling.Rescue from replication stress during mitosis.Structural basis for inhibition of DNA replication by aphidicolinInteractions of calf thymus DNA polymerase alpha with primer/templatesDNA topoisomerases participate in fragility of the oncogene RET.Fragile site instability in Saccharomyces cerevisiae causes loss of heterozygosity by mitotic crossovers and break-induced replication.Chromatin changes in the development and pathology of the Fragile X-associated disorders and Friedreich ataxia.The role of fragile sites in sporadic papillary thyroid carcinomaDNA polymerase POLQ and cellular defense against DNA damage.Oligodeoxynucleotide binding to (CTG) · (CAG) microsatellite repeats inhibits replication fork stalling, hairpin formation, and genome instability.Role of DNA secondary structures in fragile site breakage along human chromosome 10Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16DMutations M184V and Y115F in HIV-1 reverse transcriptase discriminate against "nucleotide-competing reverse transcriptase inhibitors".The role of DNA damage response pathways in chromosome fragility in Fragile X syndrome.Common Chemical Inductors of Replication Stress: Focus on Cell-Based Studies.Interplay between genetic and epigenetic factors governs common fragile site instability in cancer.Deoxynucleoside triphosphate and pyrophosphate binding sites in the catalytically competent ternary complex for the polymerase reaction catalyzed by DNA polymerase I (Klenow fragment).Polymerase and exonuclease activities in herpes simplex virus type 1 DNA polymerase are not highly coordinated.The "enemies within": regions of the genome that are inherently difficult to replicate.Protein kinase D isozymes activation and localization during mitosis.Infection with retroviral vectors leads to perturbed DNA replication increasing vector integrations into fragile sitesHomologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability.CBFB and MYH11 in inv(16)(p13q22) of acute myeloid leukemia displaying close spatial proximity in interphase nuclei of human hematopoietic stem cells.BRCA1 promotes unloading of the CMG helicase from a stalled DNA replication forkMismatch repair in human nuclear extracts. Time courses and ATP requirements for kinetically distinguishable steps leading to tightly controlled 5' to 3' and aphidicolin-sensitive 3' to 5' mispair-provoked excision.Interactions between the cell cycle and embryonic patterning in Arabidopsis uncovered by a mutation in DNA polymerase epsilon.Interplay between ATM and ATR in the regulation of common fragile site stability.Myosin 16 levels fluctuate during the cell cycle and are downregulated in response to DNA replication stress.
P2860
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P2860
DNA polymerase epsilon: aphidicolin inhibition and the relationship between polymerase and exonuclease activity.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
DNA polymerase epsilon: aphidi ...... rase and exonuclease activity.
@en
type
label
DNA polymerase epsilon: aphidi ...... rase and exonuclease activity.
@en
prefLabel
DNA polymerase epsilon: aphidi ...... rase and exonuclease activity.
@en
P356
P1433
P1476
DNA polymerase epsilon: aphidi ...... rase and exonuclease activity.
@en
P2093
P304
P356
10.1021/BI00084A025
P407
P577
1993-08-01T00:00:00Z