about
Computational immunology meets bioinformatics: the use of prediction tools for molecular binding in the simulation of the immune system.An atlas of active enhancers across human cell types and tissues.Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis.MicroRNA-941 Expression in Polymorphonuclear Granulocytes Is Not Related to Granulomatosis with Polyangiitis.Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteriesSNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization.Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types.Initiation of MLL-rearranged AML is dependent on C/EBPαImmunoGrid: towards agent-based simulations of the human immune system at a natural scale.ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design and optimization.EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas.Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionalityBloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis.C/EBPα is required for long-term self-renewal and lineage priming of hematopoietic stem cells and for the maintenance of epigenetic configurations in multipotent progenitorsERG promotes the maintenance of hematopoietic stem cells by restricting their differentiation.Oncogenic fusion proteins expressed in immature hematopoietic cells fail to recapitulate the transcriptional changes observed in human AML.MHC motif viewer.TGIF1 is a negative regulator of MLL-rearranged acute myeloid leukemia.HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis.Modelling the human immune system by combining bioinformatics and systems biology approaches.Lack of the p42 form of C/EBPα leads to spontaneous immortalization and lineage infidelity of committed myeloid progenitors.CTLs' repertoire shaping in the thymus: a Monte Carlo simulation.The MHC motif viewer: a visualization tool for MHC binding motifs.Immune system simulation online.Bistability in autoimmune diseases.Gaboxadol has affinity for the proton-coupled amino acid transporter 1, SLC36A1 (hPAT1)--A modelling approach to determine IC(50) values of the three ionic species of gaboxadol.Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies.Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients.Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucinCellular origin of prognostic chromosomal aberrations in AML patientsHemaExplorer: a Web server for easy and fast visualization of gene expression in normal and malignant hematopoiesisBloodSpot: a database of healthy and malignant haematopoiesis updated with purified and single cell mRNA sequencing profilesSimulating kinetic parameters in transporter mediated permeability across Caco-2 cells. A case study of estrone-3-sulfateLeukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates
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description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
@hy
name
Nicolas Rapin
@ast
Nicolas Rapin
@en
Nicolas Rapin
@es
Nicolas Rapin
@nl
Nicolas Rapin
@sl
type
label
Nicolas Rapin
@ast
Nicolas Rapin
@en
Nicolas Rapin
@es
Nicolas Rapin
@nl
Nicolas Rapin
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prefLabel
Nicolas Rapin
@ast
Nicolas Rapin
@en
Nicolas Rapin
@es
Nicolas Rapin
@nl
Nicolas Rapin
@sl
P106
P108
P1153
23390492100
P21
P2798
P31
P496
0000-0001-5208-8874