about
Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition.Rational design and simple chemistry yield a superior, neuroprotective HDAC6 inhibitor, tubastatin AA novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs.An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity.Bicyclic-Capped Histone Deacetylase 6 Inhibitors with Improved Activity in a Model of Axonal Charcot-Marie-Tooth DiseaseExploration of the labeling of [11C]tubastatin A at the hydroxamic acid site with [11C]carbon monoxide.Creating zinc monkey wrenches in the treatment of epigenetic disorders.An Fc domain protein-small molecule conjugate as an enhanced immunomodulator.An Fc-Small Molecule Conjugate for Targeted Inhibition of the Adenosine 2A Receptor.A selective phenelzine analogue inhibitor of histone demethylase LSD1.Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors.Second-generation histone deacetylase 6 inhibitors enhance the immunosuppressive effects of Foxp3+ T-regulatory cells.Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex.Chiral Mercaptoacetamides Display Enantioselective Inhibition of Histone Deacetylase 6 and Exhibit Neuroprotection in Cortical Neuron Models of Oxidative StressSynthesis and antitubercular activity of quaternized promazine and promethazine derivativesInvestigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse modelSite-Specific Protein Labeling with N-Hydroxysuccinimide-Esters and the Analysis of Ubiquitin Ligase MechanismsLysine-Specific Demethylase 1 Mediates AKT Activity and Promotes Epithelial-to-Mesenchymal Transition in PIK3CA-Mutant Colorectal CancerInhibiting the coregulator CoREST impairs Foxp3+ Treg function and promotes antitumor immunity
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description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Jay H Kalin
@es
Jay H. Kalin
@en
Jay H. Kalin
@sl
type
label
Jay H Kalin
@es
Jay H. Kalin
@en
Jay H. Kalin
@sl
prefLabel
Jay H Kalin
@es
Jay H. Kalin
@en
Jay H. Kalin
@sl
P106
P1153
15843779000
P21
P31
P3835
P496
0000-0002-8747-6022
P569
2000-01-01T00:00:00Z