A selective phenelzine analogue inhibitor of histone demethylase LSD1.
about
Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectivesProtein lysine acetylation by p300/CBPEpigenome-modifying tools in asthmaKDM1 class flavin-dependent protein lysine demethylasesLSD1 Histone Demethylase Assays and InhibitionSubstrate- and cofactor-independent inhibition of histone demethylase KDM4C.Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies.Cognition and mood-related behaviors in L3mbtl1 null mutant mice.Structure activity relationship and modeling studies of inhibitors of lysine specific demethylase 1Lysine-specific demethylase 1 promotes tumorigenesis and predicts prognosis in gallbladder cancer.3-(Piperidin-4-ylmethoxy)pyridine Containing Compounds Are Potent Inhibitors of Lysine Specific Demethylase 1.Epigenetic regulation of LSD1 during mammary carcinogenesis.Mining the epigenetic landscape of tissue polarity in search of new targets for cancer therapy.Medicinal chemistry insights in the discovery of novel LSD1 inhibitors.Inhibitors of Protein Methyltransferases and Demethylases.Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia.LSD1 inhibitors: a patent review (2010-2015).Inhibitors of enzymes catalyzing modifications to histone lysine residues: structure, function and activity.Insight into the binding mode of a novel LSD1 inhibitor by molecular docking and molecular dynamics simulations.Hologram quantitative structure-activity relationship and comparative molecular interaction field analysis of aminothiazole and thiazolesulfonamide as reversible LSD1 inhibitors.Histone Lysine Demethylase Inhibitors.Structural insight into inhibitors of flavin adenine dinucleotide-dependent lysine demethylases.Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors.LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer.Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex.Nickel(0)-catalyzed linear-selective hydroarylation of unactivated alkenes and styrenes with aryl boronic acids
P2860
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P2860
A selective phenelzine analogue inhibitor of histone demethylase LSD1.
description
2014 nî lūn-bûn
@nan
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
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2014年论文
@zh-cn
name
A selective phenelzine analogue inhibitor of histone demethylase LSD1.
@en
type
label
A selective phenelzine analogue inhibitor of histone demethylase LSD1.
@en
prefLabel
A selective phenelzine analogue inhibitor of histone demethylase LSD1.
@en
P2093
P2860
P50
P356
P1433
P1476
A selective phenelzine analogue inhibitor of histone demethylase LSD1.
@en
P2093
Alan J Tackett
Anne M Cieniewicz
Heather Roberson
Jeffrey Givens
Jianfei Hu
Jiang Qian
Lindsay B Avery
Nkosi Adejola
Oliver G McDonald
Philip A Cole
P2860
P304
P356
10.1021/CB500018S
P577
2014-04-07T00:00:00Z