A selective phenelzine analogue inhibitor of histone demethylase LSD1. - Wikidata - awgldk - TriplyDB

A selective phenelzine analogue inhibitor of histone demethylase LSD1.

A selective phenelzine analogue inhibitor of histone demethylase LSD1.

http://www.wikidata.org/entity/Q41514691

about

Targeting histone methylation for cancer therapy: enzymes, inhibitors, biological activity and perspectives Protein lysine acetylation by p300/CBP Epigenome-modifying tools in asthma KDM1 class flavin-dependent protein lysine demethylases LSD1 Histone Demethylase Assays and Inhibition Substrate- and cofactor-independent inhibition of histone demethylase KDM4C.Pure Diastereomers of a Tranylcypromine-Based LSD1 Inhibitor: Enzyme Selectivity and In-Cell Studies.Cognition and mood-related behaviors in L3mbtl1 null mutant mice.Structure activity relationship and modeling studies of inhibitors of lysine specific demethylase 1 Lysine-specific demethylase 1 promotes tumorigenesis and predicts prognosis in gallbladder cancer.3-(Piperidin-4-ylmethoxy)pyridine Containing Compounds Are Potent Inhibitors of Lysine Specific Demethylase 1.Epigenetic regulation of LSD1 during mammary carcinogenesis.Mining the epigenetic landscape of tissue polarity in search of new targets for cancer therapy.Medicinal chemistry insights in the discovery of novel LSD1 inhibitors.Inhibitors of Protein Methyltransferases and Demethylases.Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia.LSD1 inhibitors: a patent review (2010-2015).Inhibitors of enzymes catalyzing modifications to histone lysine residues: structure, function and activity.Insight into the binding mode of a novel LSD1 inhibitor by molecular docking and molecular dynamics simulations.Hologram quantitative structure-activity relationship and comparative molecular interaction field analysis of aminothiazole and thiazolesulfonamide as reversible LSD1 inhibitors.Histone Lysine Demethylase Inhibitors.Structural insight into inhibitors of flavin adenine dinucleotide-dependent lysine demethylases.Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors.LSD1 activation promotes inducible EMT programs and modulates the tumour microenvironment in breast cancer.Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex.Nickel(0)-catalyzed linear-selective hydroarylation of unactivated alkenes and styrenes with aryl boronic acids

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P2860

A selective phenelzine analogue inhibitor of histone demethylase LSD1.

http://www.wikidata.org/entity/Q41514691

description

2014 nî lūn-bûn

@nan

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

2014年论文

@zh

2014年论文

@zh-cn

name

A selective phenelzine analogue inhibitor of histone demethylase LSD1.

@en

type

label

A selective phenelzine analogue inhibitor of histone demethylase LSD1.

@en

prefLabel

A selective phenelzine analogue inhibitor of histone demethylase LSD1.

@en

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ACS Chemical Biology

P1476

A selective phenelzine analogue inhibitor of histone demethylase LSD1.

@en

P2093

Alan J Tackett

http://www.w3.org/2001/XMLSchema#string

Anne M Cieniewicz

http://www.w3.org/2001/XMLSchema#string

Heather Roberson

http://www.w3.org/2001/XMLSchema#string

Jeffrey Givens

http://www.w3.org/2001/XMLSchema#string

Jianfei Hu

http://www.w3.org/2001/XMLSchema#string

Jiang Qian

http://www.w3.org/2001/XMLSchema#string

Lindsay B Avery

http://www.w3.org/2001/XMLSchema#string

Nkosi Adejola

http://www.w3.org/2001/XMLSchema#string

Oliver G McDonald

http://www.w3.org/2001/XMLSchema#string

Philip A Cole

http://www.w3.org/2001/XMLSchema#string

P2860

Structural basis of LSD1-CoREST selectivity in histone H3 recognition

LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Structural basis of histone demethylation by LSD1 revealed by suicide inactivation

Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine

Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2

Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1

Molecular Mimicry and Ligand Recognition in Binding and Catalysis by the Histone Demethylase LSD1-CoREST Complex

Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b

P304

1284-1293

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scholarly article

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10.1021/CB500018S

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6

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P478

9

http://www.w3.org/2001/XMLSchema#string

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Martin S Taylor

Andrew P. Feinberg

Martin S Taylor

P577

2014-04-07T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

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261441475

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24707965

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4076021

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