Effect of DNA polymerases and high mobility group protein 1 on the carrier ligand specificity for translesion synthesis past platinum-DNA adducts.
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Differential activation of DNA-PK based on DNA strand orientation and sequence biasMitochondrial DNA damage and its consequences for mitochondrial gene expression2.4-A crystal structure of the asymmetric platinum complex [Pt(ammine)(cyclohexylamine)]2+ bound to a dodecamer DNA duplexSolution Structures of a DNA Dodecamer Duplex with and without a Cisplatin 1,2-d(GG) Intrastrand Cross-Link: Comparison with the Same DNA Duplex Containing an Oxaliplatin 1,2-d(GG) Intrastrand Cross-Link † , ‡Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-LinksThe Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) ProdrugsEnhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor agentsSatraplatin: leading the new generation of oral platinum agentsChromatin Regulates Genome Targeting with Cisplatin.Oxaliplatin: a review of evolving concepts.Novel role of base excision repair in mediating cisplatin cytotoxicity.Molecular mechanisms of resistance and toxicity associated with platinating agents.Human mitochondrial DNA polymerase γ exhibits potential for bypass and mutagenesis at UV-induced cyclobutane thymine dimers{(1R,2R,4R)-4-methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): a novel enantiomerically pure oxaliplatin derivative showing improved anticancer activity in vivo.Satraplatin: an orally available platinum analog for the treatment of cancer.ERCC1, defective mismatch repair status as predictive biomarkers of survival for stage III colon cancer patients receiving oxaliplatin-based adjuvant chemotherapyMechanism of double-base lesion bypass catalyzed by a Y-family DNA polymerase.RB signaling prevents replication-dependent DNA double-strand breaks following genotoxic insultNucleotide incorporation by human DNA polymerase gamma opposite benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyguanosine and deoxyadenosine.Epistatic role of base excision repair and mismatch repair pathways in mediating cisplatin cytotoxicityDebio 0507 primarily forms diaminocyclohexane-Pt-d(GpG) and -d(ApG) DNA adducts in HCT116 cells.Cisplatin DNA damage and repair maps of the human genome at single-nucleotide resolution.Organic cation transporters are determinants of oxaliplatin cytotoxicity.Translesion DNA synthesis in the context of cancer research.Oxaliplatin retains HMGB1 intranuclearly and ameliorates collagen type II-induced arthritis.Effects of spectator ligands on the specific recognition of intrastrand platinum-DNA cross-links by high mobility group box and TATA-binding proteins.Mitochondrial DNA maintenance: an appraisal.Platinum-(IV)-derivative satraplatin induced G2/M cell cycle perturbation via p53-p21(waf1/cip1)-independent pathway in human colorectal cancer cells.Environmental mutagens induced transversions but not transitions in regulatory region of mitochondrial DNA.Conformation of DNA GG intrastrand cross-link of antitumor oxaliplatin and its enantiomeric analog.Chiral differentiation of DNA adducts formed by enantiomeric analogues of antitumor cisplatin is sequence-dependent.Ataxia telangiectasia and rad3-related kinase contributes to cell cycle arrest and survival after cisplatin but not oxaliplatin.Molecular dynamic simulations of cisplatin- and oxaliplatin-d(GG) intrastand cross-links reveal differences in their conformational dynamicsThe effect of DNA structure on the catalytic efficiency and fidelity of human DNA polymerase beta on templates with platinum-DNA adducts.MutS preferentially recognizes cisplatin- over oxaliplatin-modified DNA.Off-Target Effects of Drugs that Disrupt Human Mitochondrial DNA Maintenance.Satraplatin (JM-216) mediates G2/M cell cycle arrest and potentiates apoptosis via multiple death pathways in colorectal cancer cells thus overcoming platinum chemo-resistance.Chemotherapeutic-Induced Cardiovascular Dysfunction: Physiological Effects, Early Detection-The Role of Telomerase to Counteract Mitochondrial Defects and Oxidative Stress.Association ofHMGB1andHMGB2genetic polymorphisms with lung cancer chemotherapy response
P2860
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P2860
Effect of DNA polymerases and high mobility group protein 1 on the carrier ligand specificity for translesion synthesis past platinum-DNA adducts.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Effect of DNA polymerases and ...... sis past platinum-DNA adducts.
@en
type
label
Effect of DNA polymerases and ...... sis past platinum-DNA adducts.
@en
prefLabel
Effect of DNA polymerases and ...... sis past platinum-DNA adducts.
@en
P2093
P356
P1433
P1476
Effect of DNA polymerases and ...... sis past platinum-DNA adducts.
@en
P2093
P304
11026-11039
P356
10.1021/BI9909187
P407
P577
1999-08-01T00:00:00Z