Enhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor agents - Wikidata - awgldk - TriplyDB

Enhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor agents

Enhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor agents

http://www.wikidata.org/entity/Q28191144

about

Hairpin structure within the 3'UTR of DNA polymerase beta mRNA acts as a post-transcriptional regulatory element and interacts with Hax-1 Gut Microbiota Imbalance and Base Excision Repair Dynamics in Colon Cancer ( R )-β,γ-Fluoromethylene-dGTP-DNA Ternary Complex with DNA Polymerase β Halogenated β,γ-Methylene- and Ethylidene-dGTP-DNA Ternary Complexes with DNA Polymerase β: Structural Evidence for Stereospecific Binding of the Fluoromethylene Analogues Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4 TCRP1 contributes to cisplatin resistance by preventing Pol β degradation in lung cancer cells An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells Structural insights on the pamoic acid and the 8 kDa domain of DNA polymerase beta complex: towards the design of higher-affinity inhibitors.Gastrointestinal hyperplasia with altered expression of DNA polymerase beta.Ribonucleoside triphosphates as substrate of human immunodeficiency virus type 1 reverse transcriptase in human macrophages Structural basis for the inefficient nucleotide incorporation opposite cisplatin-DNA lesion by human DNA polymerase β.RNA aptamers selected against DNA polymerase beta inhibit the polymerase activities of DNA polymerases beta and kappa.Involvement of DNA polymerase β overexpression in the malignant transformation induced by benzo[a]pyrene.Novel role of base excision repair in mediating cisplatin cytotoxicity.Genes and pathways driving glioblastomas in humans and murine disease models.Molecular mechanisms of resistance and toxicity associated with platinating agents.Two Scaffolds from Two Flips: (α,β)/(β,γ) CH2/NH "Met-Im" Analogues of dTTP Base excision repair-mediated resistance to cisplatin in KRAS(G12C) mutant NSCLC cells.Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice.Human methyl purine DNA glycosylase and DNA polymerase beta expression collectively predict sensitivity to temozolomide.The roles of DNA polymerase ζ and the Y family DNA polymerases in promoting or preventing genome instability.DNA Polymerase Beta Germline Variant Confers Cellular Response to Cisplatin Therapy.DNA polymerase beta promoter mutations affect gene transcription, translation and the sensitivity of esophageal cancer cells to cisplatin treatment.HAX-1 promotes the chemoresistance, invasion, and tumorigenicity of esophageal squamous carcinoma cells.Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy.DNA polymerase beta overexpression stimulates the Rad51-dependent homologous recombination in mammalian cells.Overexpression of DNA polymerase beta results in an increased rate of frameshift mutations during base excision repair.p12(CDK2-AP1) mediates DNA damage responses induced by cisplatin.Protective role of Puralpha to cisplatin.Deregulated DNA polymerase beta strengthens ionizing radiation-induced nucleotidic and chromosomal instabilities.Dysregulated Expression and Subcellular Localization of Base Excision Repair (BER) Pathway Enzymes in Gallbladder Cancer Structural and Kinetic Studies of the Effect of Guanine N7 Alkylation and Metal Cofactors on DNA Replication

P2860

Q24565017-E26B3C94-5CCE-4E76-ACBA-EC0FAE0C070A Q26740627-DDBEEA1E-D456-4032-B8E4-F01CB114C74E Q27649120-D77C2640-A2D2-4B99-80F8-55EFF44FBD9A Q27661593-886BC210-26D5-4916-8D14-A15447066DF4 Q27662057-2E273048-9087-4B6B-ACFA-F63E825A2506 Q28118898-924DD813-B867-4FC6-A57D-416028D8D5F4 Q28486021-3A49310D-978A-4C5C-B53A-30CABA85B0EA Q33328676-F6D4D5D5-79C6-4853-868C-FB87343EFCB1 Q33490616-0C513BB5-B755-41E8-8690-FAC776B19CF8 Q34386057-F5811366-922F-4F2E-8F06-E719D7AE471F Q34467599-57AFDBFC-004C-4F57-AFCF-1E1ECC167C02 Q34622845-8C4B2CF0-FD49-4AE1-A909-481BE797B0EA Q34799165-452FA24E-6E1C-4F33-8DA3-A6FA2B998EE8 Q34800428-F8969DE1-36F0-43A3-BC33-BF3321DB20D9 Q35143797-249A9FC2-2085-4132-95DC-FB43FDEBE3D9 Q35758048-83D57920-16C0-4354-AB47-837F1152C0B8 Q36355109-8E577D59-9A0A-42BC-8F83-DAD6C5D07986 Q36557507-61DF769A-ED9F-439B-B2F5-05ED853A1515 Q37052491-1E855996-D5F2-4C26-9C33-A7914536B010 Q37541592-7A4224BB-EE77-4D7D-BB89-AB605C86789A Q38063711-CBB5044F-A36D-4C56-B938-20ED237739D4 Q39028215-361CB97D-6E91-46CB-B3A5-15B6E3FE7204 Q39250722-43BF20FD-9A6A-47F4-8C69-FF6D93E7A07B Q39373450-72E1226B-4BD2-414F-A13F-E1CB322A123F Q39786191-BF1D1B37-B033-4B36-B826-BDF58CA24187 Q40156883-8D6674F2-07F7-4DB6-9D57-C20867E7781F Q40176489-B10A4AB9-B3BB-4125-B947-81C0B7B441A6 Q40492168-A2936681-4424-4358-95F4-D668EB891951 Q43143989-F6815FB5-6DFD-472B-AFAE-873650D6C9FD Q43955963-74B422D4-3D11-4972-BF77-8534E31DAFC3 Q57146599-AD7FBB01-1D40-4295-ACB5-96EB2A9DA113 Q58784820-92AB09E6-EE5A-4964-A7AC-F6BD416F7991

P2860

Enhanced expression and activity of DNA polymerase beta in human ovarian tumor cells: impact on sensitivity towards antitumor agents

http://www.wikidata.org/entity/Q28191144

description

2001 nî lūn-bûn

@nan

2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Enhanced expression and activi ...... ivity towards antitumor agents

@ast

Enhanced expression and activi ...... ivity towards antitumor agents

@en

Enhanced expression and activi ...... ivity towards antitumor agents

@nl

type

label

Enhanced expression and activi ...... ivity towards antitumor agents

@ast

Enhanced expression and activi ...... ivity towards antitumor agents

@en

Enhanced expression and activi ...... ivity towards antitumor agents

@nl

prefLabel

Enhanced expression and activi ...... ivity towards antitumor agents

@ast

Enhanced expression and activi ...... ivity towards antitumor agents

@en

Enhanced expression and activi ...... ivity towards antitumor agents

@nl

P1433

Q28191144-71A16F9D-3846-43C3-B11E-2D1C7D1370F2

P1476

Q28191144-FF9289AC-25D4-48D5-A196-562258D464F8

P2093

Q28191144-5D13413A-F65F-4FC6-A26E-92D20BC0B426

Q28191144-B2A9CCC1-01B3-4767-9D60-1078B3D5048C

Q28191144-C5EB74F3-4748-41A3-B8C3-7683FF096503

Q28191144-C78DDE3F-0421-44F5-BD5D-0712092860A1

Q28191144-DD87794C-560C-48C3-8EED-BC499438EC38

Q28191144-ECE58292-87B8-41D7-AF76-1627F7ED0933

Q28191144-EE4E36F1-7011-4235-87D5-EBD598C8774E

P2860

Q28191144-32DB0319-4EA0-43C8-94F1-BDBE1986E96D

Q28191144-38F8CBE8-E648-4CFA-B44D-CEE764C0068C

Q28191144-484CFD76-5ECD-4051-BD21-7E8E5A4FE318

Q28191144-5AA4E90D-54D7-4F9F-918E-E6CDCFC5DEB4

Q28191144-6200E023-9C06-4BF3-986E-91CC3D023900

Q28191144-7878A6C7-FCDE-44AA-88B5-6230160E4C94

Q28191144-841FA3AA-DC58-4D43-9148-9E15AB64D323

Q28191144-8EDB22F8-B893-4084-B7AB-155ECF3165B0

Q28191144-910CC407-505E-495E-B6A2-053779213ECE

Q28191144-9794039D-50FB-422F-8E51-377B897FCAA2

P2888

Q28191144-7DA3E7AB-642E-410A-8B38-61AF5B3C7208

P304

Q28191144-39CFEF1E-8343-402C-A570-62C1D2526962

P31

Q28191144-5BC4C821-DBC9-446A-94B2-082C5CDEEA26

P3181

Q28191144-5AEDBECD-D2B8-4621-9DC4-A64D8FF964C8

P356

Q28191144-C0791D93-18F6-42EF-A347-EB7EA2CC7BFE

P407

Q28191144-B9DD8AE3-CB3C-40CF-8B9C-1D1429BE2F4B

P433

Q28191144-AC5C6DD9-1AC8-4E18-8221-048883774957

P478

Q28191144-4AC18E7F-86CB-4C48-904E-95E9D8ECB426

P577

Q28191144-099EF7BC-3E3C-4696-B7FD-B6AA3AF3164D

P5875

Q28191144-B1E89C69-1325-4D76-9CB0-6DBFAFFED692

P6179

Q28191144-701A1A5A-50D4-41B4-9818-544D12C772DA

P698

Q28191144-F950D4BF-DD8A-45C9-AC55-664111E58F6B

P3181

P356

P1433

P1476

Enhanced expression and activi ...... ivity towards antitumor agents

@en

P2093

C Cazaux

http://www.w3.org/2001/XMLSchema#string

J S Hoffmann

http://www.w3.org/2001/XMLSchema#string

L Hogarth

http://www.w3.org/2001/XMLSchema#string

L Minto

http://www.w3.org/2001/XMLSchema#string

S B Howell

http://www.w3.org/2001/XMLSchema#string

V Bergoglio

http://www.w3.org/2001/XMLSchema#string

Y Canitrot

http://www.w3.org/2001/XMLSchema#string

P2860

Characterization of DNA polymerase beta mRNA: cell-cycle and growth response in cultured human cells

Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs

Fidelity and processivity of Saccharomyces cerevisiae DNA polymerase eta.

DNA polymerase beta expression differences in selected human tumors and cell lines

A plethora of lesion-replicating DNA polymerases.

DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS gene.

Fork-like DNA templates support bypass replication of lesions that block DNA synthesis on single-stranded templates.

Effect of DNA polymerases and high mobility group protein 1 on the carrier ligand specificity for translesion synthesis past platinum-DNA adducts.

Differential gene expression in human cancer cells resistant to cisplatin.

Clinical pharmacology of the 6-thiopurines.

P2888

P304

6181-7

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

4643980

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/SJ.ONC.1204743

http://www.w3.org/2001/XMLSchema#string

P407

P433

43

http://www.w3.org/2001/XMLSchema#string

P478

20

http://www.w3.org/2001/XMLSchema#string

P577

2001-09-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

238198983

http://www.w3.org/2001/XMLSchema#string

P6179

1025078569

http://www.w3.org/2001/XMLSchema#string

P698

11593426

http://www.w3.org/2001/XMLSchema#string