Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?
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Obesity and psychotic disorders: uncovering common mechanisms through metabolomicsInvestigation of 7-dehydrocholesterol reductase pathway to elucidate off-target prenatal effects of pharmaceuticals: a systematic reviewAssociation between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?LOC689986, a unique gene showing specific expression in restricted areas of the rodent neocortexDrug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: marked differences between various antipsychotic drugs.Sp1 expression is disrupted in schizophrenia; a possible mechanism for the abnormal expression of mitochondrial complex I genes, NDUFV1 and NDUFV2Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells.Effects of typical and atypical antipsychotic drugs on gene expression profiles in the liver of schizophrenia subjects.Deducing corticotropin-releasing hormone receptor type 1 signaling networks from gene expression data by usage of genetic algorithms and graphical Gaussian modelsEffect of chronic fluoxetine treatment on male and female rat erythrocyte and prefrontal cortex fatty acid composition.Relationships between the use of second-generation antipsychotics and changes in total cholesterol levels in children and adolescents perinatally infected with HIVGenetic associations of brain structural networks in schizophrenia: a preliminary studyA critical review of pro-cognitive drug targets in psychosis: convergence on myelination and inflammation.Lipid-lowering effects of tetradecylthioacetic acid in antipsychotic-exposed, female rats: challenges with long-term treatmentDifferential effects of antipsychotic medications on polyunsaturated fatty acid biosynthesis in rats: Relationship with liver delta6-desaturase expressionAtypical antipsychotic medications increase postprandial triglyceride and glucose levels in male rats: relationship with stearoyl-CoA desaturase activityAcute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat.Omega-3 fatty acid deficiency augments risperidone-induced hepatic steatosis in rats: positive association with stearoyl-CoA desaturase.Increased lactate levels and reduced pH in postmortem brains of schizophrenics: medication confoundsLack of association of SNPs from the FADS1-FADS2 gene cluster with major depression or suicidal behaviorAntipsychotic-induced increase in lipid biosynthesis: activation through inhibition?Atypical antipsychotics alter cholesterol and fatty acid metabolism in vitroCharacterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding.A potential mechanism underlying atypical antipsychotics-induced lipid disturbancesBerberine Alleviates Olanzapine-Induced Adipogenesis via the AMPKα-SREBP Pathway in 3T3-L1 Cells.Statin prescribing for people with severe mental illnesses: a staggered cohort study of 'real-world' impacts.White matter changes associated with antipsychotic treatment in first-episode psychosis.Pharmacogenomics of sterol synthesis and statin use in schizophrenia subjects treated with antipsychotics.Weight gain and changes in metabolic variables following olanzapine treatment in schizophrenia and bipolar disorder.Understanding aberrant white matter development in schizophrenia: an avenue for therapy?Pharmacogenetic Aspects of Antipsychotic Drug-induced Weight Gain - A Critical Review.Potential mechanisms of atypical antipsychotic-induced hypertriglyceridemia.A systematic review of antipsychotic drug effects on human gene expression related to risk factors for cardiovascular disease.Necroptosis-like Neuronal Cell Death Caused by Cellular Cholesterol Accumulation.A gene expression and systems pathway analysis of the effects of clozapine compared to haloperidol in the mouse brain implicates susceptibility genes for schizophrenia.Therapeutic efficacy of atypical antipsychotic drugs by targeting multiple stress-related metabolic pathways.In vivo evidence of differential impact of typical and atypical antipsychotics on intracortical myelin in adults with schizophrenia.Haloperidol induces pharmacoepigenetic response by modulating miRNA expression, global DNA methylation and expression profiles of methylation maintenance genes and genes involved in neurotransmission in neuronal cells.Overexpression of Insig-2 inhibits atypical antipsychotic-induced adipogenic differentiation and lipid biosynthesis in adipose-derived stem cells.Differential effects of typical and atypical antipsychotics on brain myelination in schizophrenia.
P2860
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P2860
Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Antipsychotic drugs activate S ...... : a novel mechanism of action?
@en
type
label
Antipsychotic drugs activate S ...... : a novel mechanism of action?
@en
prefLabel
Antipsychotic drugs activate S ...... : a novel mechanism of action?
@en
P2093
P2860
P356
P1476
Antipsychotic drugs activate S ...... : a novel mechanism of action?
@en
P2093
Stansberg C
P2860
P2888
P304
P356
10.1038/SJ.TPJ.6500323
P577
2005-01-01T00:00:00Z
P5875
P6179
1021307041