Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action? - Wikidata - awgldk - TriplyDB

Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?

Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?

http://www.wikidata.org/entity/Q38323472

about

Obesity and psychotic disorders: uncovering common mechanisms through metabolomics Investigation of 7-dehydrocholesterol reductase pathway to elucidate off-target prenatal effects of pharmaceuticals: a systematic review Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?LOC689986, a unique gene showing specific expression in restricted areas of the rodent neocortex Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: marked differences between various antipsychotic drugs.Sp1 expression is disrupted in schizophrenia; a possible mechanism for the abnormal expression of mitochondrial complex I genes, NDUFV1 and NDUFV2 Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells.Effects of typical and atypical antipsychotic drugs on gene expression profiles in the liver of schizophrenia subjects.Deducing corticotropin-releasing hormone receptor type 1 signaling networks from gene expression data by usage of genetic algorithms and graphical Gaussian models Effect of chronic fluoxetine treatment on male and female rat erythrocyte and prefrontal cortex fatty acid composition.Relationships between the use of second-generation antipsychotics and changes in total cholesterol levels in children and adolescents perinatally infected with HIV Genetic associations of brain structural networks in schizophrenia: a preliminary study A critical review of pro-cognitive drug targets in psychosis: convergence on myelination and inflammation.Lipid-lowering effects of tetradecylthioacetic acid in antipsychotic-exposed, female rats: challenges with long-term treatment Differential effects of antipsychotic medications on polyunsaturated fatty acid biosynthesis in rats: Relationship with liver delta6-desaturase expression Atypical antipsychotic medications increase postprandial triglyceride and glucose levels in male rats: relationship with stearoyl-CoA desaturase activity Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat.Omega-3 fatty acid deficiency augments risperidone-induced hepatic steatosis in rats: positive association with stearoyl-CoA desaturase.Increased lactate levels and reduced pH in postmortem brains of schizophrenics: medication confounds Lack of association of SNPs from the FADS1-FADS2 gene cluster with major depression or suicidal behavior Antipsychotic-induced increase in lipid biosynthesis: activation through inhibition?Atypical antipsychotics alter cholesterol and fatty acid metabolism in vitro Characterization of drug-induced transcriptional modules: towards drug repositioning and functional understanding.A potential mechanism underlying atypical antipsychotics-induced lipid disturbances Berberine Alleviates Olanzapine-Induced Adipogenesis via the AMPKα-SREBP Pathway in 3T3-L1 Cells.Statin prescribing for people with severe mental illnesses: a staggered cohort study of 'real-world' impacts.White matter changes associated with antipsychotic treatment in first-episode psychosis.Pharmacogenomics of sterol synthesis and statin use in schizophrenia subjects treated with antipsychotics.Weight gain and changes in metabolic variables following olanzapine treatment in schizophrenia and bipolar disorder.Understanding aberrant white matter development in schizophrenia: an avenue for therapy?Pharmacogenetic Aspects of Antipsychotic Drug-induced Weight Gain - A Critical Review.Potential mechanisms of atypical antipsychotic-induced hypertriglyceridemia.A systematic review of antipsychotic drug effects on human gene expression related to risk factors for cardiovascular disease.Necroptosis-like Neuronal Cell Death Caused by Cellular Cholesterol Accumulation.A gene expression and systems pathway analysis of the effects of clozapine compared to haloperidol in the mouse brain implicates susceptibility genes for schizophrenia.Therapeutic efficacy of atypical antipsychotic drugs by targeting multiple stress-related metabolic pathways.In vivo evidence of differential impact of typical and atypical antipsychotics on intracortical myelin in adults with schizophrenia.Haloperidol induces pharmacoepigenetic response by modulating miRNA expression, global DNA methylation and expression profiles of methylation maintenance genes and genes involved in neurotransmission in neuronal cells.Overexpression of Insig-2 inhibits atypical antipsychotic-induced adipogenic differentiation and lipid biosynthesis in adipose-derived stem cells.Differential effects of typical and atypical antipsychotics on brain myelination in schizophrenia.

P2860

Q27011617-DE55B1AB-5EC1-4F16-B156-9A8003294055 Q28078252-6B0E48C8-36B7-4237-A87C-14A1CCD709F6 Q28264722-41DEE1F7-D26E-4445-B99A-3320F023F4BC Q28676984-F22EA951-EC2F-4FF1-B94A-ECD0D989E5F7 Q33260941-BBD372DD-2419-4149-93D1-ECCA96983F8F Q33296977-ABD664C9-7078-47C6-A981-E74213458C1D Q33498169-B4B6FD39-FBF3-4DEA-AD6F-1ACE1E1FCE55 Q33503890-6DE548BC-48E0-48EE-B5A7-E2AD4C381A8B Q33751836-82AAB007-6908-4255-B707-D5671078300D Q34126331-12EB46C8-B839-4363-BE58-CAD1EEFEE771 Q34145387-E42F0CD4-4D61-45BA-ADE8-AE7C44EBF0E2 Q34343604-8B1FFA1A-6782-42D5-BB4B-949B53FBEB7A Q34405264-1B2095F5-7C27-491C-8F18-DB211DA57B64 Q34506022-CA880064-A08B-4DEC-A218-A0D61006625F Q35000399-5DCC6841-03F6-4FA1-8ED9-22172DF9B484 Q35000419-5A906D13-432F-4CDF-941D-B4058D357537 Q35675775-28494CC0-42B4-4B22-974F-95590429797C Q36164661-9EB1C4E4-B94A-4F5A-B627-812B74A42AE7 Q36528676-B9C18B01-C6A3-49D2-B605-0E08D5E0C022 Q36609756-8F8FCDD1-6C89-4696-942D-DC66C5FEEEAA Q36658336-9683003E-6351-4D11-AE1C-5BEB5B644F9D Q36658341-E1555A83-21A3-425D-BFCD-0C97E1D33238 Q36856689-603288E4-A15D-41C5-8EC8-B9D736D5F60B Q37058653-21C3E500-D1D7-4749-BCCE-3B487FFC1E5B Q37465547-B1027FEB-B3BD-435F-99EB-A0EA7D3C6B2D Q37704226-4F031C96-FBAF-4A2C-B75B-14EE0C34F35C Q37705723-E06E10F1-28F3-4720-A934-F669487F557A Q37725043-9D46EF6C-C3DB-4813-887F-A2FA4488423A Q37865505-321ED2B2-D198-4961-ACF8-6F6987B802CC Q37896626-1447CE31-A2FB-440A-B251-64967D7505FB Q38083647-66EBAE8D-1118-45FF-8DD6-7E6EE0D593B4 Q38119865-E3D0814D-36C2-4BE5-8978-4FA77F9BC05D Q38194900-458B932A-63D4-41B4-AB95-DE57455B5261 Q38290575-DE090DC9-3097-45AC-A2DE-C4C56BB6BB17 Q38496254-2650D20D-3D64-4AFB-9128-FCB81C6B7907 Q38783169-EFFA5526-692F-4DD7-B458-702ED8E1394E Q40277970-AA72DEFB-7E76-4C0B-B760-F36E73AD2242 Q41492800-17835FF9-4EC4-4436-AA74-017922C83B80 Q41541889-61993BE8-6DEE-408C-BDA8-7C4721514EFD Q42108290-F2A6A079-8F87-4272-A2AB-E9B692EE4C92

P2860

Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?

http://www.wikidata.org/entity/Q38323472

description

2005 nî lūn-bûn

@nan

2005年の論文

@ja

2005年学术文章

@wuu

2005年学术文章

@zh-cn

2005年学术文章

@zh-hans

2005年学术文章

@zh-my

2005年学术文章

@zh-sg

2005年學術文章

@yue

2005年學術文章

@zh

2005年學術文章

@zh-hant

name

Antipsychotic drugs activate S ...... : a novel mechanism of action?

@en

type

label

Antipsychotic drugs activate S ...... : a novel mechanism of action?

@en

prefLabel

Antipsychotic drugs activate S ...... : a novel mechanism of action?

@en

P1433

Q38323472-8895143C-3F58-4224-8824-4E87FAF5A425

P1476

Q38323472-A921FF3A-E192-483B-9D12-12FC50D59169

P2093

Q38323472-1014AC0F-0227-4822-AF0E-94DE1614DD57

Q38323472-3302776C-C5C9-47AA-9021-8A14789F1589

Q38323472-5BB16A3B-20C2-4A47-9A93-A4C0858E7209

Q38323472-5D8BB847-5D7D-4A1D-8EFA-0EF0778F9F1D

Q38323472-A837A260-0557-4867-A134-7A727204431E

Q38323472-AF1C0FF0-45C8-4B0F-AB0D-FD2E3C827485

Q38323472-D32D7DB0-DB73-4CFE-8EF1-14D4B2956856

Q38323472-D82C2E3F-FCB3-4AED-943C-30F2CACBCAC2

Q38323472-DCBB891D-9764-45C8-B15D-1AAEFB0A3CED

P2860

Q38323472-0A9B8853-600B-4568-987C-D6342D8CFDB4

Q38323472-0AC11673-2DF1-4E0C-9B10-180C62DEB997

Q38323472-28B17AD1-F4D8-404A-85D7-D438898B9AA5

Q38323472-2BCE88E1-573C-463A-882E-149C2074580F

Q38323472-350B15C5-3036-4849-9102-F1732CC33F4B

Q38323472-438CCE63-1A47-4165-9EAC-F2924C24D219

Q38323472-4E2B5830-3828-457A-83DB-ACEE079A50C4

Q38323472-555E69D4-0260-4426-B38C-DA13CA3BD19B

Q38323472-5B127C93-9AD6-4EFA-B0D3-56908B2FC126

Q38323472-5C4B940E-F87E-4771-98DE-47A171919142

P2888

Q38323472-20C6283E-A1CD-4A56-9AEF-8543C5A941BB

P304

Q38323472-F255F4EA-E1E8-4BF7-BC87-1F85BF8FA91E

P31

Q38323472-D4850F36-093D-44A3-AD78-000FABAADED3

P356

Q38323472-EE622A39-7B12-4BBC-8DEB-9B5D9AE49441

P433

Q38323472-F720D68B-73E2-401A-85ED-2DCF59B8813E

P478

Q38323472-B7E706DA-5F59-4D32-B20B-52AB8244C660

P50

Q38323472-3BB43D56-F8FA-4E43-A523-FFAFCD2283F0

Q38323472-D0E79617-7713-457B-BFBF-9D0CDC115D0E

P577

Q38323472-4464F9FD-0E46-4D85-B87B-7209BDD6FB0B

P5875

Q38323472-C38ABEF4-DE2A-43FD-B8FD-E3950621EAD6

P6179

Q38323472-6176D4FD-11A9-46C3-A67E-10C57F164F8A

P698

Q38323472-5EF81C66-68D1-4A29-B5F7-364B453CC20A

P356

P1433

The Pharmacogenomics Journal

P1476

Antipsychotic drugs activate S ...... : a novel mechanism of action?

@en

P2093

Berge RK

http://www.w3.org/2001/XMLSchema#string

Breilid H

http://www.w3.org/2001/XMLSchema#string

Fernø J

http://www.w3.org/2001/XMLSchema#string

Glambek M

http://www.w3.org/2001/XMLSchema#string

Løvlie R

http://www.w3.org/2001/XMLSchema#string

Raeder MB

http://www.w3.org/2001/XMLSchema#string

Skrede S

http://www.w3.org/2001/XMLSchema#string

Stansberg C

http://www.w3.org/2001/XMLSchema#string

Steen VM

http://www.w3.org/2001/XMLSchema#string

P2860

Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

Cholesterol-induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphiles

Local regulation of fat metabolism in peripheral nerves.

Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

Meta-analysis of regional brain volumes in schizophrenia.

Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia.

Progressive decrease of left Heschl gyrus and planum temporale gray matter volume in first-episode schizophrenia: a longitudinal magnetic resonance imaging study

P2888

P304

298-304

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.TPJ.6500323

http://www.w3.org/2001/XMLSchema#string

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

5

http://www.w3.org/2001/XMLSchema#string

P50

Karl J Tronstad

P577

2005-01-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7716662

http://www.w3.org/2001/XMLSchema#string

P6179

1021307041

http://www.w3.org/2001/XMLSchema#string

P698

16027736

http://www.w3.org/2001/XMLSchema#string