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Automated quantification and integrative analysis of 2D and 3D mitochondrial shape and network propertiesHyperoxic treatment induces mesenchymal-to-epithelial transition in a rat adenocarcinoma model.Hyperoxia increases the uptake of 5-fluorouracil in mammary tumors independently of changes in interstitial fluid pressure and tumor stroma.Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance.Metabolic effects of thia fatty acids.The metabolic syndrome and the hepatic fatty acid drainage hypothesis.Is targeted chemotherapy an alternative to immunotherapy in chronic lymphocytic leukemia?Subcellular Distribution of NAD+ between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells.A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphologyProtein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML.Targeting mitochondria in the treatment of human cancer: a coordinated attack against cancer cell energy metabolism and signalling.Far-infrared radiation protects viability in a cell model of Spinocerebellar Ataxia by preventing polyQ protein accumulation and improving mitochondrial functionConnexin-based signaling in acute myelogenous leukemia (AML).Regulation and quantification of cellular mitochondrial morphology and content.Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell linesTetradecylthioacetic acid inhibits growth of rat glioma cells ex vivo and in vivo via PPAR-dependent and PPAR-independent pathways.Increased hepatic mitochondrial FA oxidation reduces plasma and liver TG levels and is associated with regulation of UCPs and APOC-III in rats.Corrigendum: A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology.Peptide-mediated delivery of donor mitochondria improves mitochondrial function and cell viability in human cybrid cells with the MELAS A3243G mutation.In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacylglycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation.Protein kinase A activators and the pan-PPAR agonist tetradecylthioacetic acid elicit synergistic anti-leukaemic effects in AML through CREB.Growth reduction in glioma cells after treatment with tetradecylthioacetic acid: changes in fatty acid metabolism and oxidative status.Optimization of methods and treatment conditions for studying effects of fatty acids on cell growth.Human TNF-alpha in transgenic mice induces differential changes in redox status and glutathione-regulating enzymes.Antiproliferative effects of a non-beta-oxidizable fatty acid, tetradecylthioacetic acid, in native human acute myelogenous leukemia blast cultures.Impact of mitochondrial beta-oxidation in fatty acid-mediated inhibition of glioma cell proliferation.Changed energy state and increased mitochondrial beta-oxidation rate in liver of rats associated with lowered proton electrochemical potential and stimulated uncoupling protein 2 (UCP-2) expression: evidence for peroxisome proliferator-activated recMitochondrial-targeted fatty acid analog induces apoptosis with selective loss of mitochondrial glutathione in promyelocytic leukemia cells.BMET-34DRUG REPURPOSING DISCOVERS BETA-SITOSTEROL AS AN EFFECTIVE THERAPEUTIC AGENT AGAINST MELANOMA BRAIN METASTASES IN VIVO.Long term treatment with tetradecylthioacetic acid improves the antioxidant status in obese Zucker (fa/fa) rats.The angiogenic switch leads to a metabolic shift in human glioblastoma.In vitro culture of human osteosarcoma cell lines: a comparison of functional characteristics for cell lines cultured in medium without and with fetal calf serum.Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomideIntroducing nano-scale quantitative polymerase chain reactionA Bioactively Modified Fatty Acid Improves Survival and Impairs Metastasis in Preclinical Models of Acute LeukemiaNeural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and FunctionalityEpithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC.Metabolic effects of 3-thia fatty acid in cancer cellsPoorly oxidizable fatty acid analogues inhibit the proliferation of cancer cells in culture
P50
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P50
description
Noors onderzoeker
@nl
hulumtues
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researcher
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հետազոտող
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name
Karl J Tronstad
@ast
Karl J Tronstad
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Karl J Tronstad
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Karl J Tronstad
@nl
Karl J Tronstad
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type
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Karl J Tronstad
@ast
Karl J Tronstad
@en
Karl J Tronstad
@es
Karl J Tronstad
@nl
Karl J Tronstad
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prefLabel
Karl J Tronstad
@ast
Karl J Tronstad
@en
Karl J Tronstad
@es
Karl J Tronstad
@nl
Karl J Tronstad
@sl
P106
P21
P27
P31
P496
0000-0003-3496-3123