HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma.
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Genome wide prediction of HNF4alpha functional binding sites by the use of local and global sequence contextThe mechanisms of human hotdog-fold thioesterase 2 (hTHEM2) substrate recognition and catalysis illuminated by a structure and function based analysisCoordinate regulation of lipid metabolism by novel nuclear receptor partnershipsDivergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor developmentThe nuclear receptor hepatocyte nuclear factor 4alpha acts as a morphogen to induce the formation of microvilliThe LIM and SH3 domain protein family: structural proteins or signal transducers or both?Expression of HNF4alpha in the human and rat choroid plexus: implications for drug transport across the blood-cerebrospinal-fluid (CSF) barrierDissection of the transformation of primary human hematopoietic cells by the oncogene NUP98-HOXA9Improved conditional expression systems resulting in physiological level of HNF4alpha expression confirm HNF4alpha induced apoptosis in the pancreatic beta-cell line INS-1.Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways.TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors.A high resolution genome-wide scan of HNF4α recognition sites infers a regulatory gene network in colon cancer.Double conditional human embryonic kidney cell line based on FLP and ΦC31 mediated transgene integration.Decreased selenium-binding protein 1 mRNA expression is associated with poor prognosis in renal cell carcinomaRNA-Seq of human breast ductal carcinoma in situ models reveals aldehyde dehydrogenase isoform 5A1 as a novel potential target.Fraternal twins: Swiprosin-1/EFhd2 and Swiprosin-2/EFhd1, two homologous EF-hand containing calcium binding adaptor proteins with distinct functions.Selenoprotein P regulation by the glucocorticoid receptorDifferences in gastric carcinoma microenvironment stratify according to EBV infection intensity: implications for possible immune adjuvant therapy.Predicting tissue specific transcription factor binding sites.A unique four-hub protein cluster associates to glioblastoma progression.A systematic analysis of the 3'UTR of HNF4A mRNA reveals an interplay of regulatory elements including miRNA target sites.Extensive decoupling of metabolic genes in cancer.Impairment of hepatic nuclear factor-4α binding to the Stim1 promoter contributes to high glucose-induced upregulation of STIM1 expression in glomerular mesangial cellsMdm2 is a novel activator of ApoCIII promoter which is antagonized by p53 and SHP inhibitionAging Selectively Modulates Vitamin C Transporter Expression Patterns in the Kidney.Nuclear receptor hepatocyte nuclear factor 4alpha1 competes with oncoprotein c-Myc for control of the p21/WAF1 promoter.Differential transcriptomic analysis of spontaneous lung tumors in B6C3F1 mice: comparison to human non-small cell lung cancer.Elevated NCOR1 disrupts a network of dietary-sensing nuclear receptors in bladder cancer cellsHepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium.Gene expression signatures differentiate ovarian/peritoneal serous carcinoma from breast carcinoma in effusions.TGF-beta-dependent and -independent roles of STRAP in cancer.An integrative functional genomics approach for discovering biomarkers in schizophrenia.Role of hepatocyte nuclear factor 4α (HNF4α) in cell proliferation and cancer.Synthetic Biology Platform for Sensing and Integrating Endogenous Transcriptional Inputs in Mammalian CellsA cross-species approach to identify transcriptional regulators exemplified for Dnajc22 and Hnf4a.GATA4 loss of function in liver cancer impedes precursor to hepatocyte transition.Regulatory feedback loops bridge the human gene regulatory network and regulate carcinogenesis.Differentiation therapy and the mechanisms that terminate cancer cell proliferation without harming normal cells
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P2860
HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
HNF4alpha reduces proliferatio ...... lated in renal cell carcinoma.
@en
type
label
HNF4alpha reduces proliferatio ...... lated in renal cell carcinoma.
@en
prefLabel
HNF4alpha reduces proliferatio ...... lated in renal cell carcinoma.
@en
P2093
P2860
P356
P1433
P1476
HNF4alpha reduces proliferatio ...... lated in renal cell carcinoma.
@en
P2093
Belén Lucas
Gerhart U Ryffel
Jörn Lausen
Karen Grigo
Ludger Klein-Hitpass
Silke Erdmann
P2860
P2888
P304
P356
10.1038/SJ.ONC.1208794
P407
P577
2005-09-01T00:00:00Z
P5875
P6179
1007599642