An essential splicing factor, SLU7, mediates 3' splice site choice in yeast.
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Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicingSplicing factor hSlu7 contains a unique functional domain required to retain the protein within the nucleusCharacterization and cloning of the human splicing factor 9G8: a novel 35 kDa factor of the serine/arginine protein familyHuman homologs of yeast prp16 and prp17 reveal conservation of the mechanism for catalytic step II of pre-mRNA splicingThe HeLa 200 kDa U5 snRNP-specific protein and its homologue in Saccharomyces cerevisiae are members of the DEXH-box protein family of putative RNA helicasesEvidence that U5 snRNP recognizes the 3' splice site for catalytic step II in mammalsBone morphogenetic protein-4-induced activation of Xretpos is mediated by Smads and Olf-1/EBF associated zinc finger (OAZ).Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiaeAn upstream AG determines whether a downstream AG is selected during catalytic step II of splicingIdentification and characterisation of a developmentally regulated mammalian gene that utilises -1 programmed ribosomal frameshiftingEvidence for a Prp24 binding site in U6 snRNA and in a putative intermediate in the annealing of U6 and U4 snRNAsA novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reactionLarge-scale proteomic analysis of the human spliceosomeCrystal structure of the functional domain of the splicing factor Prp18Extensive genetic interactions between PRP8 and PRP17/CDC40, two yeast genes involved in pre-mRNA splicing and cell cycle progression.Evidence for a role of Sky1p-mediated phosphorylation in 3' splice site recognition involving both Prp8 and Prp17/Slu4.How Slu7 and Prp18 cooperate in the second step of yeast pre-mRNA splicing.Mutational analysis identifies two separable roles of the Saccharomyces cerevisiae splicing factor Prp18.Mutational analysis of the PRP4 protein of Saccharomyces cerevisiae suggests domain structure and snRNP interactions.Synthetic lethality of yeast slt mutations with U2 small nuclear RNA mutations suggests functional interactions between U2 and U5 snRNPs that are important for both steps of pre-mRNA splicing.Prp22, a DExH-box RNA helicase, plays two distinct roles in yeast pre-mRNA splicingFunctional interactions between Prp8, Prp18, Slu7, and U5 snRNA during the second step of pre-mRNA splicing.Identification of Prp40, a novel essential yeast splicing factor associated with the U1 small nuclear ribonucleoprotein particlePrp8 retinitis pigmentosa mutants cause defects in the transition between the catalytic steps of splicing.Rapid screening of yeast mutants with reporters identifies new splicing phenotypes.The yeast splicing factor Prp40p contains functional leucine-rich nuclear export signals that are essential for splicingFunctional association of essential splicing factor(s) with PRP19 in a protein complex.The carboxy terminal WD domain of the pre-mRNA splicing factor Prp17p is critical for function.Malleable ribonucleoprotein machine: protein intrinsic disorder in the Saccharomyces cerevisiae spliceosome.Alternative Splicing in Next Generation Sequencing Data of Saccharomyces cerevisiae.The genetic control of neocortex volume and covariation with neocortical gene expression in mice.SF3b1 mutations associated with myelodysplastic syndromes alter the fidelity of branchsite selection in yeastGenetic and functional interaction of evolutionarily conserved regions of the Prp18 protein and the U5 snRNA.Interaction of the yeast DExH-box RNA helicase prp22p with the 3' splice site during the second step of nuclear pre-mRNA splicingCharacterization and functional ordering of Slu7p and Prp17p during the second step of pre-mRNA splicing in yeast.Identification of a human protein that recognizes the 3' splice site during the second step of pre-mRNA splicing.The RNA splicing factor hSlu7 is required for correct 3' splice-site choice.Role of the 3' splice site in U12-dependent intron splicingMutagenesis of the yeast gene PRP8 reveals domains governing the specificity and fidelity of 3' splice site selection.Conservation of functional domains involved in RNA binding and protein-protein interactions in human and Saccharomyces cerevisiae pre-mRNA splicing factor SF1
P2860
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P2860
An essential splicing factor, SLU7, mediates 3' splice site choice in yeast.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
An essential splicing factor, SLU7, mediates 3' splice site choice in yeast.
@en
type
label
An essential splicing factor, SLU7, mediates 3' splice site choice in yeast.
@en
prefLabel
An essential splicing factor, SLU7, mediates 3' splice site choice in yeast.
@en
P356
P1433
P1476
An essential splicing factor, SLU7, mediates 3' splice site choice in yeast.
@en
P2093
P304
P356
10.1101/GAD.6.11.2112
P577
1992-11-01T00:00:00Z