TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria - Wikidata - awgldk - TriplyDB

TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

http://www.wikidata.org/entity/Q38325201

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Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch PKCδ stabilizes TAp63 to promote cell apoptosis Regulation of p63 isoforms by snail and slug transcription factors in human squamous cell carcinoma Tumor suppressors: enhancers or suppressors of regeneration?Mechanisms of transcriptional repression of cell-cycle G2/M promoters by p63.Tumor suppression in skin and other tissues via cross-talk between vitamin D- and p53-signaling The microRNA feedback regulation of p63 in cancer progression DNA damage response genes and the development of cancer metastasis The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice Dysregulated ΔNp63α inhibits expression of Ink4a/arf, blocks senescence, and promotes malignant conversion of keratinocytes OTX2 regulates the expression of TAp63 leading to macular and cochlear neuroepithelium development.Role of p63 and the Notch pathway in cochlea development and sensorineural deafness Differences in the transactivation domains of p53 family members: a computational study.TAp63 suppress metastasis via miR-133b in colon cancer cells.Regulation of p63 protein stability via ubiquitin-proteasome pathway.p63 transcriptionally regulates the expression of matrix metallopeptidase 13.Gene bi-targeting by viral and human miRNAs NAD(P)H quinone oxidoreductase protects TAp63gamma from proteasomal degradation and regulates TAp63gamma-dependent growth arrest.Combining Oncolytic Virotherapy with p53 Tumor Suppressor Gene Therapy ∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites.Interactions of the p53 protein family in cellular stress response in gastrointestinal tumors TAp63 is a transcriptional target of NF-kappaB.Targeting of p53-transcriptional dysfunction by conditionally replicating adenovirus is not limited by p53-homologues.TAp63 induces senescence and suppresses tumorigenesis in vivo.The role of mutant p53 in human cancer.Phospho-ΔNp63α/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposure.Inhibition of pluripotent stem cell-derived teratoma formation by small molecules Metabolic effect of TAp63α: enhanced glycolysis and pentose phosphate pathway, resulting in increased antioxidant defense p53 Family and Cellular Stress Responses in Cancer.ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage DeltaNp63alpha confers tumor cell resistance to cisplatin through the AKT1 transcriptional regulation Functional p53 is required for rapid restoration of daunorubicin-induced lesions of the spleen Preclinical evaluation of 4-methylthiobutyl isothiocyanate on liver cancer and cancer stem cells with different p53 status Poly (C)-binding protein 1 regulates p63 expression through mRNA stability.Toll-like receptor 3 (TLR3) induces apoptosis via death receptors and mitochondria by up-regulating the transactivating p63 isoform alpha (TAP63alpha).The E3 ubiquitin ligase Itch controls the protein stability of p63 p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53.Tumor protein p63/nuclear factor κB feedback loop in regulation of cell death.

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P2860

TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

http://www.wikidata.org/entity/Q38325201

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2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

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type

label

TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

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prefLabel

TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

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SJ.EMBOJ.7600708

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The EMBO Journal

P1476

TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

@en

P2093

Andreas Koch

http://www.w3.org/2001/XMLSchema#string

Anna Maria Lena

http://www.w3.org/2001/XMLSchema#string

Eleonora Candi

http://www.w3.org/2001/XMLSchema#string

Elisa Schulze Schleithoff

http://www.w3.org/2001/XMLSchema#string

Gerry Melino

http://www.w3.org/2001/XMLSchema#string

Henning Schulze-Bergkamen

http://www.w3.org/2001/XMLSchema#string

Katja Lorenz

http://www.w3.org/2001/XMLSchema#string

Maria Valeria Catani

http://www.w3.org/2001/XMLSchema#string

Martina Müller

http://www.w3.org/2001/XMLSchema#string

Olav Gressner

http://www.w3.org/2001/XMLSchema#string

P2860

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

TRAF-interacting protein (TRIP): a novel component of the tumor necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappaB activation

Cloning and functional analysis of human p51, which structurally and functionally resembles p53

Structure-function analysis of an evolutionary conserved protein, DAP3, which mediates TNF-alpha- and Fas-induced cell death

A simplified system for generating recombinant adenoviruses

Minimum information about a microarray experiment (MIAME)-toward standards for microarray data

Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome

A GTP-binding adapter protein couples TRAIL receptors to apoptosis-inducing proteins

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2458-2471

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10.1038/SJ.EMBOJ.7600708

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13

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24

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Alessandro Terrinoni

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2005-06-09T00:00:00Z

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7797152

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15944736

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apoptotic process

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1173149

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