Editing of glutamate receptor subunit B pre-mRNA by splice-site variants of interferon-inducible double-stranded RNA-specific adenosine deaminase ADAR1.
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Antiviral actions of interferonsHuman RNA-specific adenosine deaminase ADAR1 transcripts possess alternative exon 1 structures that initiate from different promoters, one constitutively active and the other interferon inducibleRNA editing by adenosine deaminases that act on RNARNA-specific adenosine deaminase ADAR1 suppresses measles virus-induced apoptosis and activation of protein kinase PKRAdenosine deaminases acting on RNA (ADARs) are both antiviral and proviralDimerization of ADAR2 is mediated by the double-stranded RNA binding domainc-Jun amino-terminal kinase-1 mediates glucose-responsive upregulation of the RNA editing enzyme ADAR2 in pancreatic beta-cellsIntracellular localization of differentially regulated RNA-specific adenosine deaminase isoforms in inflammationPsychiatric clearance for patients started on interferon-alpha-based therapies.An RNA editor, adenosine deaminase acting on double-stranded RNA (ADAR1).Effects of conserved RNA secondary structures on hepatitis delta virus genotype I RNA editing, replication, and virus productionCRM1 mediates the export of ADAR1 through a nuclear export signal within the Z-DNA binding domain.Reovirus-mediated induction of ADAR1 (p150) minimally alters RNA editing patterns in discrete brain regions.Tipping the balance: antagonism of PKR kinase and ADAR1 deaminase functions by virus gene products.dADAR, a Drosophila double-stranded RNA-specific adenosine deaminase is highly developmentally regulated and is itself a target for RNA editing.Adenosine deaminases acting on RNA, RNA editing, and interferon action.Inflammatory cytokine-associated depressionHost response to polyomavirus infection is modulated by RNA adenosine deaminase ADAR1 but not by ADAR2Chimeric double-stranded RNA-specific adenosine deaminase ADAR1 proteins reveal functional selectivity of double-stranded RNA-binding domains from ADAR1 and protein kinase PKR.Distinct in vivo roles for double-stranded RNA-binding domains of the Xenopus RNA-editing enzyme ADAR1 in chromosomal targeting.Activity-regulated RNA editing in select neuronal subfields in hippocampus.Editing of Cellular Self-RNAs by Adenosine Deaminase ADAR1 Suppresses Innate Immune Stress ResponsesOrganization of the mouse RNA-specific adenosine deaminase Adar1 gene 5'-region and demonstration of STAT1-independent, STAT2-dependent transcriptional activation by interferon.Inflammatory cytokines in depression: neurobiological mechanisms and therapeutic implications.Risk for depression during interferon-alpha treatment is affected by the serotonin transporter polymorphism.ZFAT gene variant association with multiple sclerosis in the Arabian Gulf population: A genetic basis for gender-associated susceptibilityAdenosine deaminase ADAR1 increases gene expression at the translational level by decreasing protein kinase PKR-dependent eIF-2alpha phosphorylation.RNA adenosine deaminase ADAR1 deficiency leads to increased activation of protein kinase PKR and reduced vesicular stomatitis virus growth following interferon treatment.Aberrant overexpression of ADAR1 promotes gastric cancer progression by activating mTOR/p70S6K signaling.Activity regulation of adenosine deaminases acting on RNA (ADARs).RNA Editing, ADAR1, and the Innate Immune Response.RNA editing by ADAR2 is metabolically regulated in pancreatic islets and beta-cells.GluA2 is rapidly edited at the Q/R site during neural differentiation in vitro.A high-throughput screen to identify enhancers of ADAR-mediated RNA-editing.Expression of interferon-inducible RNA adenosine deaminase ADAR1 during pathogen infection and mouse embryo development involves tissue-selective promoter utilization and alternative splicing.
P2860
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P2860
Editing of glutamate receptor subunit B pre-mRNA by splice-site variants of interferon-inducible double-stranded RNA-specific adenosine deaminase ADAR1.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Editing of glutamate receptor ...... fic adenosine deaminase ADAR1.
@en
type
label
Editing of glutamate receptor ...... fic adenosine deaminase ADAR1.
@en
prefLabel
Editing of glutamate receptor ...... fic adenosine deaminase ADAR1.
@en
P2860
P356
P1476
Editing of glutamate receptor ...... fic adenosine deaminase ADAR1.
@en
P2860
P304
P356
10.1074/JBC.274.8.5070
P407
P577
1999-02-01T00:00:00Z