Role of a major autoepitope in forming the DNA binding site of the p70 (Ku) antigen.
about
Isolation of Ku70-binding proteins (KUBs)Autoantibodies define a family of proteins with conserved double-stranded RNA-binding domains as well as DNA binding activityMapping of protein-protein interactions within the DNA-dependent protein kinase complexInteraction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acidsEpstein-Barr virus-induced autoimmune responses. II. Immunoglobulin G autoantibodies to mimicking and nonmimicking epitopes. Presence in autoimmune diseaseComplementation of the ionizing radiation sensitivity, DNA end binding, and V(D)J recombination defects of double-strand break repair mutants by the p86 Ku autoantigen.Ku80 removal from DNA through double strand break-induced ubiquitylation.Autoimmunity and apoptosisKu70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo.Autoantibodies to intracellular autoantigens and their B-cell epitopes: molecular probes to study the autoimmune response.Role of Ku70 and Bax in epigallocatechin-3-gallate-induced apoptosis of A549 cells in vivo.Modulation of thermal induction of hsp70 expression by Ku autoantigen or its individual subunits.Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86.Random phage mimotopes recognized by monoclonal antibodies against the pyruvate dehydrogenase complex-E2 (PDC-E2).Defining the minimal domain of Ku80 for interaction with Ku70.In vivo association of Ku with mammalian origins of DNA replication.Production and characterization of recombinant human Ku antigen.Inhibition of Ku heterodimer DNA end binding activity during granulocytic differentiation of human promyelocytic cell lines.Asymmetric nature of two subunits of RAD18, a RING-type ubiquitin ligase E3, in the human RAD6A-RAD18 ternary complex.Double-strand break repair by Ku70 requires heterodimerization with Ku80 and DNA binding functions.Characterization of a Ku86 variant protein that results in altered DNA binding and diminished DNA-dependent protein kinase activity.The DNA-dependent protein kinase, DNA-PK: 10 years and no ends in sight.Ku80-deleted cells are defective at base excision repair.The role of the SAP motif in promoting Holliday junction binding and resolution by SpCCE1.
P2860
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P2860
Role of a major autoepitope in forming the DNA binding site of the p70 (Ku) antigen.
description
1992 nî lūn-bûn
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1992年の論文
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1992年学术文章
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1992年学术文章
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1992年学术文章
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1992年学术文章
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1992年学术文章
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1992年學術文章
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1992年學術文章
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1992年學術文章
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name
Role of a major autoepitope in forming the DNA binding site of the p70 (Ku) antigen.
@en
type
label
Role of a major autoepitope in forming the DNA binding site of the p70 (Ku) antigen.
@en
prefLabel
Role of a major autoepitope in forming the DNA binding site of the p70 (Ku) antigen.
@en
P2093
P2860
P356
P1476
Role of a major autoepitope in forming the DNA binding site of the p70 (Ku) antigen.
@en
P2093
P2860
P304
P356
10.1084/JEM.175.6.1677
P407
P577
1992-06-01T00:00:00Z