Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells.
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Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuityFibroblast growth factor (FGF) homologous factors share structural but not functional homology with FGFsReceptor specificity of the fibroblast growth factor familySyndecans: multifunctional cell-surface co-receptorsFibroblast growth factorsAnalysis of mutations in fibroblast growth factor (FGF) and a pathogenic mutation in FGF receptor (FGFR) provides direct evidence for the symmetric two-end model for FGFR dimerizationThe cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancerAntisense targeting of perlecan blocks tumor growth and angiogenesis in vivoSuppression of autocrine and paracrine functions of basic fibroblast growth factor by stable expression of perlecan antisense cDNAHeparan sulphate synthetic and editing enzymes in ovarian cancerGlypican-1 is frequently overexpressed in human gliomas and enhances FGF-2 signaling in glioma cellsReceptor specificity of the fibroblast growth factor family. The complete mammalian FGF familyAn Amino Acid Substitution in the Coding Region of the E2 Glycoprotein Adapts Ross River Virus To Utilize Heparan Sulfate as an Attachment MoietyStructure and stability of an acidic fibroblast growth factor from Notophthalmus viridescensDimerization effect of sucrose octasulfate on rat FGF1Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1Structure of a heparin-linked biologically active dimer of fibroblast growth factorMolecular and clinical significance of fibroblast growth factor 2 (FGF2 /bFGF) in malignancies of solid and hematological cancers for personalized therapiesMapping ligand binding domains in chimeric fibroblast growth factor receptor molecules. Multiple regions determine ligand binding specificityExpression and biological activity of mouse fibroblast growth factor-9Identification and characterization of a novel member of the fibroblast growth factor familyMolecular mechanisms of fibroblast growth factor signaling in physiology and pathologyHeparan sulfate proteoglycans as regulators of fibroblast growth factor-2 receptor binding in breast carcinomasMultiple consequences of a single amino acid pathogenic RTK mutation: the A391E mutation in FGFR3A splice variant of CD44 expressed in the apical ectodermal ridge presents fibroblast growth factors to limb mesenchyme and is required for limb outgrowthAssociation of hepatic lipase with proteoglycans stimulates the production of proteoglycans in vivo and in vitroProx1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesisStimulation of fibroblast growth factor receptor-1 occupancy and signaling by cell surface-associated syndecans and glypicanTargeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse modelsNMR structure of the first Ig module of mouse FGFR1Glycomics approaches for the bioassay and structural analysis of heparin/heparan sulphatesCellular signaling by fibroblast growth factors (FGFs) and their receptors (FGFRs) in male reproduction.Fibroblast growth factor 2 induced proliferation in osteoblasts and bone marrow stromal cells: a whole cell modelThe site of action of neuronal acidic fibroblast growth factor is the organ of Corti of the rat cochlea.Fibroblast growth factors 1 and 2 are distinct in oligomerization in the presence of heparin-like glycosaminoglycans.Development of a high throughput screening assay for inhibitors of fibroblast growth factor-receptor-heparin interactions.Novel 'phage display antibodies identify distinct heparan sulfate domains in developing mammalian lung.YKL-40, a marker of simian immunodeficiency virus encephalitis, modulates the biological activity of basic fibroblast growth factor.Biologically active fibroblast growth factor 1 tagged with various epitopes.A Network Map of FGF-1/FGFR Signaling System.
P2860
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P2860
Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
Heparin is required for cell-f ...... or mitogenesis in whole cells.
@en
type
label
Heparin is required for cell-f ...... or mitogenesis in whole cells.
@en
prefLabel
Heparin is required for cell-f ...... or mitogenesis in whole cells.
@en
P2093
P2860
P356
P1476
Heparin is required for cell-f ...... or mitogenesis in whole cells.
@en
P2093
P2860
P304
P356
10.1128/MCB.12.1.240
P407
P577
1992-01-01T00:00:00Z