Bypass of glycan-dependent glycoprotein delivery to ERAD by up-regulated EDEM1.
about
EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming stepThe role of EDEM2 compared with EDEM1 in ricin transport from the endoplasmic reticulum to the cytosolUnfolded Protein Response and Macroautophagy in Alzheimer's, Parkinson's and Prion DiseasesModulation of the unfolded protein response by the human hepatitis B virusThe delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiologyTyrosinase degradation is prevented when EDEM1 lacks the intrinsically disordered regionA Golgi-localized mannosidase (MAN1B1) plays a non-enzymatic gatekeeper role in protein biosynthetic quality control.Elevated systemic expression of ER stress related genes is associated with stress-related mental disorders in the Detroit Neighborhood Health StudyActivation of ERAD pathway by human hepatitis B virus modulates viral and subviral particle production.Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins.Mammalian ER mannosidase I resides in quality control vesicles, where it encounters its glycoprotein substrates.ER stress-induced eIF2-alpha phosphorylation underlies sensitivity of striatal neurons to pathogenic huntingtinHydrophobicity of protein determinants influences the recognition of substrates by EDEM1 and EDEM2 in human cells.Role of pro-oncogenic protein disulfide isomerase (PDI) family member anterior gradient 2 (AGR2) in the control of endoplasmic reticulum homeostasis.Flagging and docking: dual roles for N-glycans in protein quality control and cellular proteostasis.Cleaning up: ER-associated degradation to the rescue.Inhibition of endoplasmic reticulum associated degradation reduces endoplasmic reticulum stress and alters lysosomal morphology and distribution.Up-regulation of endoplasmic reticulum stress induced genes of the unfolded protein response in the liver of periparturient dairy cows.Specificity and regulation of the endoplasmic reticulum-associated degradation machinery.The Role of Lectin-Carbohydrate Interactions in the Regulation of ER-Associated Protein Degradation.Herp coordinates compartmentalization and recruitment of HRD1 and misfolded proteins for ERAD.Novel function of the endoplasmic reticulum degradation-enhancing α-mannosidase-like proteins in the human hepatitis B virus life cycle, mediated by the middle envelope protein.Soluble forms of polyQ-expanded huntingtin rather than large aggregates cause endoplasmic reticulum stress.A shared endoplasmic reticulum-associated degradation pathway involving the EDEM1 protein for glycosylated and nonglycosylated proteins.Inducible nitric oxide synthase is a major intermediate in signaling pathways for the survival of plasma cells.Mannosidase activity of EDEM1 and EDEM2 depends on an unfolded state of their glycoprotein substrates
P2860
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P2860
Bypass of glycan-dependent glycoprotein delivery to ERAD by up-regulated EDEM1.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
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2011年學術文章
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name
Bypass of glycan-dependent glycoprotein delivery to ERAD by up-regulated EDEM1.
@en
type
label
Bypass of glycan-dependent glycoprotein delivery to ERAD by up-regulated EDEM1.
@en
prefLabel
Bypass of glycan-dependent glycoprotein delivery to ERAD by up-regulated EDEM1.
@en
P2093
P2860
P356
P1476
Bypass of glycan-dependent glycoprotein delivery to ERAD by up-regulated EDEM1.
@en
P2093
Bella Groisman
Gerardo Z Lederkremer
Julia Leitman
Marina Shenkman
Yana Izenshtein
P2860
P304
P356
10.1091/MBC.E10-12-0944
P577
2011-09-14T00:00:00Z