Mutating a region of HIV-1 reverse transcriptase implicated in tRNA(Lys-3) binding and the consequences for (-)-strand DNA synthesis.
about
The connection domain in reverse transcriptase facilitates the in vivo annealing of tRNALys3 to HIV-1 genomic RNAHIV Genome-Wide Protein Associations: a Review of 30 Years of ResearchInability of human immunodeficiency virus type 1 produced in murine cells to selectively incorporate primer formula.Identification of specific HIV-1 reverse transcriptase contacts to the viral RNA:tRNA complex by mass spectrometry and a primary amine selective reagentStructural basis for the specificity of the initiation of HIV-1 reverse transcription.Assembly, purification and crystallization of an active HIV-1 reverse transcriptase initiation complex.Formation of the tRNALys packaging complex in HIV-1.Human immunodeficiency virus type-1 reverse transcription can be inhibited in vitro by oligonucleotides that target both natural and synthetic tRNA primers.Initiation of HIV Reverse TranscriptionA nucleotide substitution in the tRNA(Lys) primer binding site dramatically increases replication of recombinant simian immunodeficiency virus containing a human immunodeficiency virus type 1 reverse transcriptase.Structural features of tRNALys favored by anticodon nuclease as inferred from reactivities of anticodon stem and loop substrate analogs.Correlation between tRNALys3 aminoacylation and its incorporation into HIV-1.Functional characterization of chimeric reverse transcriptases with polypeptide subunits of highly divergent HIV-1 group M and O strains.
P2860
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P2860
Mutating a region of HIV-1 reverse transcriptase implicated in tRNA(Lys-3) binding and the consequences for (-)-strand DNA synthesis.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Mutating a region of HIV-1 rev ...... for (-)-strand DNA synthesis.
@en
type
label
Mutating a region of HIV-1 rev ...... for (-)-strand DNA synthesis.
@en
prefLabel
Mutating a region of HIV-1 rev ...... for (-)-strand DNA synthesis.
@en
P2093
P2860
P356
P1476
Mutating a region of HIV-1 rev ...... for (-)-strand DNA synthesis.
@en
P2093
P2860
P304
14523-14532
P356
10.1074/JBC.273.23.14523
P407
P577
1998-06-01T00:00:00Z