Mutations in HIV reverse transcriptase which alter RNase H activity and decrease strand transfer efficiency are suppressed by HIV nucleocapsid protein
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HIV Genome-Wide Protein Associations: a Review of 30 Years of ResearchComplexes of HIV-1 RT, NNRTI and RNA/DNA hybrid reveal a structure compatible with RNA degradationSequences in the 5' and 3' R elements of human immunodeficiency virus type 1 critical for efficient reverse transcriptionZinc finger structures in the human immunodeficiency virus type 1 nucleocapsid protein facilitate efficient minus- and plus-strand transferMolecular requirements for human immunodeficiency virus type 1 plus-strand transfer: analysis in reconstituted and endogenous reverse transcription systems.Human immunodeficiency virus type 1 central DNA flap: dynamic terminal product of plus-strand displacement dna synthesis catalyzed by reverse transcriptase assisted by nucleocapsid protein.Ty3 integrase is required for initiation of reverse transcriptionStructural features in the HIV-1 repeat region facilitate strand transfer during reverse transcription.Human immunodeficiency virus type 1 nucleocapsid zn(2+) fingers are required for efficient reverse transcription, initial integration processes, and protection of newly synthesized viral DNA.The twenty-nine amino acid C-terminal cytoplasmic domain of poliovirus 3AB is critical for nucleic acid chaperone activity.Role of HIV-1 nucleocapsid protein in HIV-1 reverse transcription.Expression of an Mg2+-dependent HIV-1 RNase H construct for drug screeningMutagenesis of human immunodeficiency virus reverse transcriptase p51 subunit defines residues contributing to vinylogous urea inhibition of ribonuclease H activity.Copy-choice recombination by reverse transcriptases: reshuffling of genetic markers mediated by RNA chaperones.A mimic of HIV-1 nucleocapsid protein impairs reverse transcription and displays antiviral activity.A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.Zinc finger function of HIV-1 nucleocapsid protein is required for removal of 5'-terminal genomic RNA fragments: a paradigm for RNA removal reactions in HIV-1 reverse transcription.Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mg2+.Examining the role of the HIV-1 reverse transcriptase p51 subunit in positioning and hydrolysis of RNA/DNA hybridsThe remarkable frequency of human immunodeficiency virus type 1 genetic recombinationVariation of human immunodeficiency virus type-1 reverse transcriptase within the simian immunodeficiency virus genome of RT-SHIV.Unreported intrinsic disorder in proteins: Building connections to the literature on IDPs.Protein intrinsic disorder as a flexible armor and a weapon of HIV-1.Recent patents and emerging therapeutics for HIV infections: a focus on protease inhibitors.Acceptor RNA cleavage profile supports an invasion mechanism for HIV-1 minus strand transfer.Mutating a region of HIV-1 reverse transcriptase implicated in tRNA(Lys-3) binding and the consequences for (-)-strand DNA synthesis.Comparison of second-strand transfer requirements and RNase H cleavages catalyzed by human immunodeficiency virus type 1 reverse transcriptase (RT) and E478Q RT.RNase H requirements for the second strand transfer reaction of human immunodeficiency virus type 1 reverse transcription.Requirements for minus-strand transfer catalyzed by Rous sarcoma virus reverse transcriptase.A nucleotide substitution in the tRNA(Lys) primer binding site dramatically increases replication of recombinant simian immunodeficiency virus containing a human immunodeficiency virus type 1 reverse transcriptase.The mechanism of actinomycin D-mediated inhibition of HIV-1 reverse transcription.Functional organization of repeat addition processivity and DNA synthesis determinants in the human telomerase multimer.Evidence of interactions between the nucleocapsid protein NCp7 and the reverse transcriptase of HIV-1.Substrate requirements for secondary cleavage by HIV-1 reverse transcriptase RNase H.Mutating conserved residues in the ribonuclease H domain of Ty3 reverse transcriptase affects specialized cleavage events.RNA degradation and primer selection by Moloney murine leukemia virus reverse transcriptase contribute to the accuracy of plus strand initiation.The annealing of tRNA3Lys to human immunodeficiency virus type 1 primer binding site is critically dependent on the NCp7 zinc fingers structure.Nucleotide excision repair and template-independent addition by HIV-1 reverse transcriptase in the presence of nucleocapsid protein.Mechanisms that prevent template inactivation by HIV-1 reverse transcriptase RNase H cleavages.Probing contacts between the ribonuclease H domain of HIV-1 reverse transcriptase and nucleic acid by site-specific photocross-linking.
P2860
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P2860
Mutations in HIV reverse transcriptase which alter RNase H activity and decrease strand transfer efficiency are suppressed by HIV nucleocapsid protein
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Mutations in HIV reverse trans ...... ed by HIV nucleocapsid protein
@ast
Mutations in HIV reverse trans ...... ed by HIV nucleocapsid protein
@en
type
label
Mutations in HIV reverse trans ...... ed by HIV nucleocapsid protein
@ast
Mutations in HIV reverse trans ...... ed by HIV nucleocapsid protein
@en
prefLabel
Mutations in HIV reverse trans ...... ed by HIV nucleocapsid protein
@ast
Mutations in HIV reverse trans ...... ed by HIV nucleocapsid protein
@en
P2093
P2860
P356
P1476
Mutations in HIV reverse trans ...... ed by HIV nucleocapsid protein
@en
P2093
C E Cameron
S F Le Grice
S J Benkovic
P2860
P304
P356
10.1073/PNAS.94.13.6700
P407
P577
1997-06-01T00:00:00Z