Leptin rapidly suppresses insulin release from insulinoma cells, rat and human islets and, in vivo, in mice.
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Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob miceRecent advances in understanding leptin signaling and leptin resistanceGlucose-stimulated insulin response in pregnant sheep following acute suppression of plasma non-esterified fatty acid concentrationsPancreatic regulation of glucose homeostasisObesity, Oxidative Stress, Adipose Tissue Dysfunction, and the Associated Health Risks: Causes and Therapeutic StrategiesLeptin induces inflammation-related genes in RINm5F insulinoma cellsDisorders of glucose metabolism in sleep apnea.SLEEP DISORDERED BREATHING AND METABOLIC EFFECTS: EVIDENCE FROM ANIMAL MODELSAn islet in distress: β cell failure in type 2 diabetes.The role of leptin in glucose homeostasis.An acute method to test leptin responsiveness in rats.Restoration of Lepr in β cells of Lepr null mice does not prevent hyperinsulinemia and hyperglycemiaCyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodentsIdentification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity.An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorptionAltered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines.Histamine regulation in glucose and lipid metabolism via histamine receptors: model for nonalcoholic steatohepatitis in miceLeptin suppression of insulin secretion and gene expression in human pancreatic islets: implications for the development of adipogenic diabetes mellitus.Nutrient sensing, leptin and insulin action.Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human isletsMetabolic consequences of intermittent hypoxia: relevance to obstructive sleep apneaThe adipocytokine Nampt and its product NMN have no effect on beta-cell survival but potentiate glucose stimulated insulin secretion.Adiposity and β-cell function: relationships differ with ethnicity and ageLeptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice.Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasisLoss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1Therapeutic impact of leptin on diabetes, diabetic complications, and longevity in insulin-deficient diabetic miceLeptin ameliorates ischemic necrosis of the femoral head in rats with obesity induced by a high-fat diet.Effects of different acute hypoxic regimens on tissue oxygen profiles and metabolic outcomesLack of association between impaired glucose tolerance and appetite regulating hormones in patients with obstructive sleep apneaLeptin in human physiology and pathophysiology.Association between plasma leptin levels and diabetes mellitusSite-specific circadian expression of leptin and its receptor in human adipose tissue.Challenges and opportunities of defining clinical leptin resistanceLipoatrophic diabetes in Irs1(-/-)/Irs3(-/-) double knockout mice.Sex differences in the regulation of body weight.Enhanced GLP-1- and sulfonylurea-induced insulin secretion in islets lacking leptin signaling.Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice.Limited impact on glucose homeostasis of leptin receptor deletion from insulin- or proglucagon-expressing cellsProlonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cells
P2860
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P2860
Leptin rapidly suppresses insulin release from insulinoma cells, rat and human islets and, in vivo, in mice.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Leptin rapidly suppresses insu ...... islets and, in vivo, in mice.
@en
type
label
Leptin rapidly suppresses insu ...... islets and, in vivo, in mice.
@en
prefLabel
Leptin rapidly suppresses insu ...... islets and, in vivo, in mice.
@en
P2093
P2860
P356
P1476
Leptin rapidly suppresses insu ...... islets and, in vivo, in mice.
@en
P2093
Gardiner JV
Kulkarni RN
Withers DJ
P2860
P304
P356
10.1172/JCI119818
P407
P577
1997-12-01T00:00:00Z